TRICHOPHYTONEAE 491 



based on a ease from Ceylon briefly described, withont reference to earlier 

 literature, by Castellani. Later reported by Castellani to be the rarest of the 

 three species causing tinea imbricata. 



In scales, cells cylindric, 2.5-3/x, rather longer from cultures, only arthro- 

 spores produced. In cultures the hyphae are septate, 3-4.5/a in diameter, di- 

 chotomous. Chlamydospores terminal, 6-9/t, or lateral, occasionally inter- 

 calary. On lactose agar, cells more irregular in shape and chlamydospores of 

 greater diameter, 18-21/a. 



On 4% glucose agar, growth abundant, cerebriform or crinkled, dirty 

 white becoming light amber or bright brown, with no velvet. On Sabouraud 

 maltose agar, growth very scanty, light gray, mostly submerged, with small 

 central knob, the submerged portion firmly embedded with deep projections, 

 color of medium unchanged. Mannite and adonite agar similar to glucose 

 agar, but growth less abundant and lighter in color. Sucrose gives the most 

 luxuriant growth, similar to glucose agar. Glycerol, nutrose, plain, maltose, 

 galactose, fructose, raffinose, and inulin agars similar to Sabouraud agar. On 

 potato, a gray white uneven mass, elevated 5-6 mm. above the surface with 

 colony only 8 mm. in diameter. Gelatin slowly liquefied. Sugars not fer- 

 mented nor acid produced. A sediment, but no pellicle, in liquid media. 



Nieuwenhuis (1898) reports successful human inoculations and gives a clear 

 account of the development of the lesions. Castellani (1910) and Hanawa & 

 Nagai (1917) also reported human inoculation. Ota & Kawatsure who con- 

 sider this organism the same as E. indicum report that they succeeded in 

 inoculating guinea pigs with three strains, the lesions being of the endothrix 

 microide type. 



Endodermophyton indicum Castellani, Jour. Trop. Med. Hyg. 14: 81-83, 

 146, 1911. 



Arthrosporia indica Grigorakis, Ann. Sci. Nat. Bot. X, 7: 414, 1925. 



Achorion (Endodermophyto7i) indicum Guiart & Grigorakis, Lyon Med. 

 141:377,1928. 



Endodermophyton concentricum Ota & Kawatsure (pro parte), Ann. Para- 

 sitol. Hum. Comp. 9 : 144-161, Pis. 2, 3, 1931. 



Frequently isolated from tinea imbricata in Malaysia. 



Mycelium of cells up to 5/a, spherical becoming ovoid or even cylindric. 

 As the mycelium ages, the cells become detached as thick-walled arthrospores. 

 Other hyphae, somewhat larger in diameter, have the ends of the cells slightly 

 inflated, suggesting the mycelium of some species of Madurella. A few slender 

 hyphae may be seen. All cells observed are 2-5-nucleate. Germination of arthro- 

 spores similar to that of chlamydospores in other dermatophytes. 



Growth slow, surface powdery, white, either with central knob or furrowed, 

 not deepening in medium. On 4% glucose agar, growth fairly abundant, sur- 

 face convoluted or furrowed, central portion deep orange, pinkish orange, or 

 reddish orange, the rest of the colony white and powdery with a short delicate 

 velvet. On sucrose and other sugar media, cerebriform, covered with a white 

 velvet. On glycerol, growth abundant, yellowish or amber ; partly covered by 



