ASPERGILLACEAE GoO 



7 months. On egg albumen, growth is feeble, graniilai-, greenisli brown. 

 Conidia not produced on peptone agar without sugar. 



Mackinnon (1932) refers this species to A. flavus Link. 



Doubtful Species 



There is little to distinguish Sterigmatocystis tropicalis Matta, Bol. Inst. 

 Brasil. Sci. 3: 51-54, 2 figs., 1927, from Aspergillus tunetanus, except its ver- 

 milion color. It was isolated from ulcerous lesions on the back of the foot, 

 removed surgically. 



PENICILLIUM 



Penicillium Link, Mag. Ges. Naturf. Freunde Berlin 3: 17, 1809. 



The type species is Penicillium expansum Link. 



Vegetative mycelium abundant, entirely submerged or more or less effused, 

 monopodially branching, septate, commonly showing vegetative anastomoses, 

 colorless or secondarily colored by products of metabolism wdiicli frequently 

 also discolor the substratum, never with hyphal walls brown or black; colonies 

 greenish or less commonly colorless, hazel, yellow, reddish, purplish or other 

 shades ; conidiophores arising- as branches from the vegetative mj^celium, fre- 

 quently perpendicular to the vegetative hyphae, but not showing differen- 

 tiated foot cells as in Aspergillus, with walls in some species smooth, in others 

 more or less conspicuously pitted or roughened from secondary thickening ; 

 conidial apparatus forming a brush or broom, the penicillus, ranging from a 

 single terminal verticil of conidiiferous cells or phialides or a terminal verticil 

 of equal branches or metulae, bearing phialides in verticils ; phialides bearing 

 single unbranched chains of conidia, each cut off as a cylindric segment from 

 an apical tube ; conidia cylindric to ovoid, ellipsoid or commonly finally 

 spherical, smooth or roughened, hyaline or variously colored, especially in 

 mass; sclerotium or peritliecium formation known only in a few species. 



While Penicillium is frequently mentioned in medical literature, there are 

 cnl^' two references where the organism has been sufficiently described to 

 be sure that it belongs in this genus. With the exception of P. mycetomato- 

 gerium and P. Bertai, none of the descriptions are adequate to permit identifica- 

 tion of a modern culture as probably belonging to them. In general, it seems 

 that the imperfectly described organism was picked up as a contaminant, and 

 there is a probability of pathogenicity in only one of the cases cited. 



Penicillium Bertai Talice & Mackinnon, Ann. Parasitol. Hum. Comp. 7: 

 97-106, 1929. 



Isolated from case of chronic pseudotuberculosis on three successive occa- 

 sions. Not pathogenic for rabbit and guinea pig. 



]\Iycelium rampant, hyaline at first becoming yellow, about 2.5/x in di- 

 ameter (2-4), with a tendency to become funiculose. Conidiophore erect, 

 20-90// X 2/^, tip enlarged to 3.2 ( 2-4.5 )/i terminated by up to 5 phialides, about 

 9 X 2.2|u, (6-16 X 1.5-3.5), which produce chains of conidia up to 20/*. Conidia 

 smooth, spherical, 1.7-3.5/x in diameter (Fig. 102). 



