632 MEDICAL MYCOLOGY 



dant, greenish yellow, each having a variable number of asci with 8 ascospores 

 per ascus. Spores grooved and crested, the latter visible but not very distinct. 

 Perithecia 34-102ju in diameter (mean 68/x) ; asci 7.6-11.4/x, in maximum diameter 

 (mean IO.6/1.) ; ascospores 5.45 x 3.75/t. Optimum temperature for growth 

 25°-30° C. 



On glucose peptone agar a diffusible yellow pigment is formed. Gelatin 

 is not liquefied within 10 days. 



Aspergillus Fontoynonti Gueguen, C. R. Soc. Biol. 66: 1052, 1053, 1909; 

 67: 10-12, 1909; Arch, de Parasitol. 14: 177-192, 1911. 



Isolated from secondary abscesses in the cervical region of a European 

 resident in Madagascar, not from "nodosites juxta-articulaires" as first re- 

 ported by an epistolary error. Abscess was on indurated base in the hypo- 

 derma, nearly painless, about the size of a large nut. Full case history given. 

 Medication with 2 gm. KI per diem for several months successful. Intravenous 

 or intraperitoneal injection into rabbits, guinea pigs, or pigeons gave negative 

 results. 



Conidiophores about 150-200/x high, excipuliform, subcontinuous, 14-18/* 

 in diameter. Phialides of flask shape, 8-12 x 2/a, giving rise to chains of 10 

 to 30 glaucous conidia which are spherical to ovoid, 4-6 x 3-5/i,, more or less 

 covered with extremely fine warts. Conidia in short flammiform plumes, 

 rarely cylindric. Early subcultures with heads proliferating and very irregu- 

 lar. Later subcultures more regular, optimum temperature 22°-25° C, no 

 growth at 37° C. 



On gelatin, there is visible growth by the fourth day with variable glau- 

 cescence. On agar, growth with less glaucescence, culture becoming greenish 

 gray. On potato, punctiform colonies appear on the fifth day and become 

 confluent on the ninth, show few conidiophores and remain dirty white. On 

 glycerol potato, growth less abundant and white. On carrot, growth visible 

 the fourth day, pale glaucescence the eighth, with finally a large elevated 

 cushion. On Jerusalem artichoke, culture turns green on the eighth day and 

 color is somewhat deeper in 3 weeks. No growth on Raulin's normal medium. 

 On Raulin's neutral medium, punctiform colonies appear on fourteenth day 

 with grayish, circular covering the third week. On Raulin's normal gelatin, 

 very small star-shaped colonies appear on the tenth to twelfth days, fruiting 

 in 3 weeks, greenish white. On Raulin's neutral gelatin, growth better, no 

 liquefaction after 40 days. In peptone broth, fructifications in 12 days, glau- 

 cous color third week. Coagulated albumen shows white punctiform colonies 

 on the eighteenth day and thereafter is stationary for one month. Organism 

 grows on a variety of sugars but best on maltose. It hydrates urea with feeble 

 formation of NH3. Milk is coagulated in 12 days, with curd subsequently 

 digested into a citron yellow liquid with light chalky sediment. Plain gelatin 

 liquefied after a month. 



Aspergillus malignus (Lindt) Thom & Church, Aspergilli 132, 1926. 



Eurotium. malignum Lindt, Arch. Exp. Path. Pharm. 25: 256-271, Figs. 

 1-11, 1889. 



