ASPERGILLACEAE 641 



cillate, umbellate, 50-60/x beyond bifurcation. Primary phialides 7.5-1.2/x long, 

 secondary phialides splierico-depressed, 3.7/1. in diameter. Conidia spherical, 

 2.2-3. 7/A, smooth, hyaline, aeruginous greenish, never long catenulate. 



Growth on glycerol or Sabouraud agar from isolation, colonies round, 

 slightly umbilicate, grayish white or gray, velvety, hyphae radiating from 

 the middle, finally giving a hemispheric effect. On potato, bread, sugar car- 

 rot, glycerol carrot, or orange, colonies ragged, floccose, moderately rugose 

 or undulate, completely covering the substrate, at first white then, on appear- 

 ance of fructifications, aeruginous green and mouse color. Reverse cream 

 colored, with edge blackening in age. No odor. On pear and apple, an 

 arachnoid colony is formed. Colony on gelatin is round, plane, slightly 

 ochraceous. In bean decoction, with or without sugar or glycerol, growth is 

 at first immersed, with the formation of a basal veil of hyphae, which are 

 hyaline, septate, 1.5-2/x in diameter, with intercalary chlamydospores, the lat- 

 ter ovoid, 8-12/A in diameter. Later there appears a supernatant pellicle with 

 normal conidiophores and hyphae. Litmus agar is turned slightly alkaline. 

 Gelatin not liquefied. 



Penicillium Giordano! Vuillemin, Champ. Parasit. 62, 1931. 



P. glaucum Giordano, Annali. Med. Nav. Colon. 24: 567, 1918, non aliorum. 



Producing fatal pseudotuberculosis. 



I have been unable to see a copy of this work. 



Penicillium minimum Siebenmann, Die Schimmelmykosen der mensch- 

 lichen Ohres. 82, 83, 1889. 



Penicilliumdhnlich Bezold, Arch. Ohrheilk. 25: 1885. 



Isolated from a case of catarrh of the middle ear following scarlet fever. 

 Three years later the organism was found abundantly fruiting in epidermis 

 and a large, crouplike membrane. 



Mycelium 2/t in diameter. Conidiophores up to 20/a long, septa 6/t apart. 

 Conidia 2.5-3/a in diameter and about the color of those in Aspergillus niger. 



The case cited by Buscino & Cardia appears somewhat doubtful. The fig- 

 ures suggest an Aspergillus, although the organism was determined by Pollacci 

 as P. minimum. 



Penicillium crustaceum [Linne] Fries, Syst. Myc. 3 : 407, 1832. 



Mucor crustaceus Linne, Species Plantarum, 1186, 1753. 



Monilia digitata Persoon, Syn. Fung. 693, 1801. 



Penicilliiim glaucum Link, Mag. Ges. Naturf. Freunde Berlin 3: 17, 1809. 



Greco, Origine des Tumeurs . . . 67-122, 1916, reports this species as the 

 etiologic agent in 3 cases. He gives much detail, but absolutely no evidence 

 that the organism cultivated was the etiologic agent or that the Penicillium 

 isolated was this species. The cases were undoubted mycoses and showed sep- 

 tate, occasionally binucleate mycelium but he was consistently unable to re- 

 produce in animals with his cultivated organism either the lesions produced 

 by 'inoculations with uncontaminated pus from the human lesions or the 

 lesions as they appear in human subjects. 



