ASPERGILLACEAE 



647 



manner, indefinite heads of conidia whieh adhere in chains, are ovoid with 

 unequal ends, 3-4 x 1.5-2/x, indefinite in number. In okl cultures there are 

 Avhite, creamy formations which may be undeveloped perithecia. Spores 

 brownish and terminated with a filiform papilla. 



On Sabouraud maltose, growth attains a diameter of 1-1.5 cm. in 8 days, 

 is round, flat, with indentations on the periphery. Central portion pure white, 

 periphery gray like gray rubber. Finally, center becomes cratoriform and 

 the periphery develops radial folds. On glycerol agar slant, growth is more 

 rapid, brighter, ivory in color, and with broader convolutions. On glycerol 

 and potato, groAvth is good and about the color of the substrate with a surface 

 of furry papillae, becoming snow white in the drier parts of the culture. 



Scopulariopsis minimus Sartory, Hufschmitt & Meyer, Bull. Acad. Med. 

 Ill, 103: 604-606, 1930. 



Isolated from a case of onychomycosis. 



Mycelium slender, 1.25-2.5|a in diameter, hyaline, branched. Conidiophores 

 10 X l-2fi, often grouped in bundles. Phialides 3.75-4.5 x 1.25-1.5;u,, sometimes 

 in groups of two to three. Conidia spherical, apiculate, 1.25-1. 5/^ in diameter. 

 Perithecia not found. Optimum temperature 28°-32° C. 



Colony crateriform, small, white, after 21 days pale green, then deep green, 

 then ashy with the margin remaining white. 



Scopulariopsis ivorensis Boucher, Bull. Soc. Path. Exot. 11: 308-321, 1918. 

 Several lesions over bony areas on each of 16 cases in Africa. Cured by 

 medication with KI. Lesions reproduced on pigeon and guinea pig from each 

 ease encountered. 



Hyphae septate with cells of metacarpal form, 1/a in diameter. Conidio- 

 phores short, irregular with long phialides. Conidia rounded or truncate, G/j. 

 in long axis, brownish, ecliinulate, thick-walled. Live 5 months in culture. 

 Gram-negative. 



All cultures reported for 25° C. in diffuse light. On poor Sabouraud 

 agar, growth powdery on the third day, chestnut on the fifth, deep brown on 

 the seventh. On simple glucose agar on the third, colonies filamentous and 

 rounded with central point refringent, browning on the fourth day, becoming 

 powdery on the fifth and chestnut colored. Giant colony is 5 mm. in diameter 

 on the second day, 1 cm. on the third day, central zone white and filamentous, 

 outer hyaline and radiate, 5 cm. in diameter on seventh day, on eighth day 

 whole colony becomes chestnut colored, on tenth dry and powdery, chestnut 

 by reflected light, black filamentous by transmitted light; growth stops the 

 twelfth day. If several inoculations have been made, colonies are. not eon- 

 fluent. On potato, second day white, filamentous colonies, third day dry, light 

 brown membrane with white border which spreads. Sixth day, culture wholly 

 chestnut. On potato glycerol, second day culture white and dry, third day 

 light brown, fourth day folded, fifth day powdery, medium covered on the 

 eleventh day. Growth is slower in the dark. In glucose bouillon colony shows 

 white clots on the surface the second day, on the fourth day a floating chest- 

 nut mat, elevated, with simple white border. 



