682 MEDICAL MYCOLOGY 



Madurella Ramiroi Piraja da Silva, Brasil Med. 33: 81-83, 1919; Mem. 

 Inst. Butantan 1: 187-207, Pis. 34-38, 1918-1919. 



Isolated from a black grain Madura foot in Brazil. The author was unable 

 to reproduce lesions in pigeons, rats, or bats. 



Mycelium moniliform, cells about 2.7/a in diameter; there are slender my- 

 celium producing chlamydospores (intercalary) and moniliform mycelium. 

 Large spherical cells, 22/* in diameter, seen in the sclerotia are probably large 

 chlamydospores similar to those in the grains from lesions. 



On Sabouraud glucose, and maltose agars, growth rather rapid, colonies 

 deep brown, cerebriform with abundant pigment formation. Sclerotia rare. 

 Colonies on yam dark gray in the center, with ashy margins. On sweet potato, 

 growth better than on banana (de terra). The culture media blacken as the 

 colonies age. On carrot, growth is grayish ashy, with irregular verrucose 

 surface. Growth best on potato, colonies ochraceous with medium darkening. 

 In potato decoction, tufts of mycelium with small black granules. In hay 

 infusion, there are formed white tufts which adhere to the walls of the tubes 

 and later there are small grains (sclerotia) similar to those from the lesions. 



Madurella Oswaldoi Parreiras Horta, A Pathologia Geral Nos. 1-4, 1919, 

 [quoted by Gammel 1926, Fonseca 1930, Froes 1930]. 



Organism shows a luxuriant mycelium which changes its color during 

 growth from greenish gray to purplish gray, becoming purplish when old. 

 No sclerotia seen in cultures. 



Cultures show a central knob with a deep depression and a zone of deep 

 fissures. Growth rapid on all media. On Sabouraud media, colonies are white 

 to dirty yellow and purple ; with sugar media, either liquid or solid, darkening. 



Madurella algiris (Blanchard) Dodge, n. comb. 



Oospora Tozeuri var. Brault & Masselot, Soc. Chirurg. April, 1911 ; Arch, 

 de Parasitol. 15: 218-225, 1912. 



Discomyces algiris Blanchard. 



Oospora algirus Sartory, Champ. Parasit. Homme Anim. 777, 778, 1923. 



Isolated from a tumor on the foot of a young Arab fifteen years old. 

 Tumor just behind the space between first and second toes, size of a large 

 nut, surface thin and ready to burst. On puncture, there was exuded a reddish 

 viscous liquid Avith black grains varying in size from that of a pinhead to 

 that of a grain of wheat. Cavity lined with a thick, soft, brownish tissue. 

 KI was not tolerated. Patient treated frequently with tincture of iodine until 

 cured. Organism not pathogenic to laboratory animals. 



In grains, mycelium septate with large intercalary chlamydospores 7 x 

 12fx in diameter. Hyphae B/x in diameter, cells 5.5-8/x long. 



Growth good on glucose and glucose glycerol agar. Colonies grayish 

 white with concentric rings of growth, center browning and folding. In age 

 it appears as a dry yellow membrane from deep chamois to tinder, with medium 

 becoming black or caramel in color. On potato, growth is poor, colony dirty 

 white, with medium blackening. On carrot, especially with glycerol, growth 



