792 MEDICAL MYCOLOGY 



11/A. Growth good on blood agar or potato. JSmall colonies on serum, partially 

 liquefying the substrate. Milk coagulated and partially digested. Gelatin 

 not liquefied. 



Trichosporium Gammeli (Pollacci & Nannizzi) Dodge, n. comb. 



Glenospora Gammeli Pollacci & Nannizzi in Blankenhorn & Gammel, Jour. 

 Clin. Invest. 4: 471-484, 9 figs., 1927. [Case history by Blankenhorn and Gam- 

 mel, Trans. Assoc. Amer. Physicians 41: 268-282, 9 figs., 1926.] 



Isolated from a case of generalized mycosis involving lungs, digestive 

 tract (?), and the epidermis, the latter with small furuncles and much necro- 

 sis, the others without either inflammation or necrosis but showing larger and 

 deeper nodules, which soften and ulcerate as in blastomycosis. Symptoms dis- 

 appeared in 61 days on medication with KI and neoarsphenamine. Nt) recur- 

 rence in 2 years. Organism not pathogenic to monkeys, guinea pigs, or rabbits. 



Sterile liyphae hyaline or subhyaline, often guttulate, continuous when 

 young, becoming septate in age, 2-5. 3/a in diameter. Cells 15-100/t long, mono- 

 podially branched, never dichotomous, larger ones frequently septate, com- 

 posed of clavate cells as in Microsporinn Audoiiini, sometimes fasciculate, here 

 and there anastomosing. Fertile hyphae concolorous, decumbent, a little more 

 slender, with short branches and with aleurospores. Aleurospores sessile 

 on aleurophores of variable length, spherical, smooth, 3.3-6/x. in diameter, at 

 first hyaline and chlorine colored, later 10-12/a in diameter, thick-walled, gran- 

 ulose, pale luteofuscus. Chlamydospores spherical to irregular, 10-12/t in di- 

 ameter, brown. Nodular organs resembling perithecia formed, but develop- 

 ment stops here. Growth strictly aerobic, optimum temperature being 18°- 

 22° C. 



Growth on Sabouraud glucose agar a dense, thick, and rather undifferen- 

 tiated felt of delicate hyphae, sometimes with slight concentric zones, white 

 to light brown and yellowish brown, 2.6-3.2 cm. across in 3 weeks. On Sabou- 

 raud maltose agar, colony is white and growth slower. Best growth on Grlitz 

 malt agar, with colony brown in color. Grayish white on peptone agar and 

 white on most other media. Upper portions of carbohydrate media darken 

 slightly. In liquid media, powder-puft'-like growths appear at the bottom and 

 rise to the top, forming a thick pellicle. In milk, only surface growth, with 

 alkaline reaction produced. In 8 weeks, milk finally clears with calcium 

 oxalate and calcium acid phosphate crystals deposited. Solution is deep yel- 

 low brown in color, with light brown growth in upper third and coarse, heavy, 

 flocculent precipitate on the bottom appearing in old cultures. Litmus broth 

 with galactose, glucose, or fructose very slowly decolorized. No fermentation. 

 Gelatin is liquefied in 3-4 weeks, with dense yellow mycelium on surface and 

 fine sediment. 



Var. lanug^nosus (Castellani) Dodge, n. comb. 



Blastomycoides lanuginosus Castellani, Brit. Jour. Derm. Syphilis 42: 365- 

 374, 1930. 



Glenospora lanuginosa Agostini, Jour. Trop. Med. Hyg. 34: 287, 288, 1931. 



