556 MEDICAL MYCOLOGY 



Oidium Quinckeanum Zopf, Die Pilze 481, 1890. 



?Achorion Arloini Biisquet, Ann. Microgr. 3: 9-21, 62-75, 136-149, Pis. 2-4, 

 1891 (see p. 507 of this book). 



Achorion eiiryihrix Neebe & Unna, Monatsh. Prakt. Derm. 16: 17-81, 

 57-92, 1893. 



Achorion Quinckeanum Bodin, Arch, de Parasitol 5: 5-30, 1902. 



Malassezia sp. Eseomel, Bull. Soc. Path. Exot. 12: 350-353, 1919. 



Malassezia muris Eseomel, Bull. Soc. Path. Exot. 17: 922, 923, 1924. 



Sahouraudites (Closiermnma) Qninckeavu>< Ota & Lanp-eron, Ann. Para- 

 sitol. Hum. Comp. 1 : 329, 1923. 



Closteroaleurosporia Qirivckeana Grigorakis, Ann. Sci. Nat. Bot. X, 7: 412, 

 1925. 



Microsporum (Closteroaleurosporia) Quinckeanum, Guiart & Grigorakis, 

 Lyon Med. 141: 377, 1928. 



This species presents many problems. It is very difficult in the early 

 eases to be sure whether the authors were dealing with accidental inocula- 

 tions of mice by A. Schoenleini or by this organism. Even the descriptions of 

 the early cultures leave us in doubt, but since the lesions on mice are more 

 severe and more common, reaching epizootic proportions, when caused by 

 this species, it seems quite probable that the early workers, such as Bennett 

 (1842), Draper (1854), Friedrich (1857), Gluge & d'Ukedem (1857), Pieschel 

 & Voigtlander (1857), Zander (1858), and Schrader (1858) were dealing with 

 this species. The statements regarding morphology are extremely contradic- 

 tory. Quincke, Busquet, Sabouraud, and Grigorakis figure closterospores, 

 Bodin does not mention them, while Langeron & Milochevitch deny that clos- 

 terospores are produced on any medium. 



Producing severe favie lesions on mice, usually attacking the head and 

 largely destroying the skin and the cornea, causing death by starvation, fol- 

 lowing blindness. Found also on a hedgehog (herisson) which had been em- 

 ployed to rid an infested house of mice. Easily inoculable into man, in whom 

 the lesions are usually confined to the glabrous skin, usually with few favie 

 crusts, so that the human lesion might be diagnosed as herpes circinatus. Micro- 

 scopically indistinguishable from Achorion Schoenleini in the tissues. Inocu- 

 lable into guinea pig, producing either favie scutula or dry scaly lesions which 

 heal spontaneously. Common in Germany, occasional in England, Austria, and 

 Hungary, rare in France. 



In hair, hyphae 1.5-2/x in diameter, arthrospores 3-6/x in diameter. In cul- 

 tures closterospores septate, walls thick, 40-70/*, 4-7-celled (3-6 septate) ; chlamy- 

 dospores 7-10/*, rarely up to 15/i ; aleurospores 4-5/1, borne on compound thyrses. 

 Langeron & Milochevitch report spirals on straw and dung. 



Colony a pure white disc resembling pleomorphic colonies even in the pri- 

 mary colony, with a short marginal fringe, becoming rough, with more or less 

 concentric furrows, with some irregular hills and channels around the margin; 

 reverse yellowish white at room temperature, deep violet at 35° C. On malt 

 agar (3% maltose and 3% carbohydrates, expressed as glucose), colony more 



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