TRICHOPHYTONEAE 



561 



Producing witkop or dikwakwadi in syphilitic natives in Bechuanaland ; for 

 description of lesions see p. 443. Inoculable to mice where lesion causes pru- 

 ritus, minute papules, the exudate causes several hairs to adhere and after a 

 time a grayish white powderj^ dust occurs about the edge of the lesion. The 

 scratching caused by the pruritus prevents the typical white scutulum from 

 developing. The fungus was reisolated from the experimental lesions. 



Arthrospores isodiametric, cylindric, invading hair follicle, while medium 

 is moist and colony young, suggesting colliform colonies etched with fine 

 wavy lines. After 10-12 days fine snow white filaments, coarse and white as 

 if dusted with dry lime. Slight growth downward into the medium, making 

 the colony very adherent to the medium. 



Mitchell & Robertson argue that it is not syphilitic in origin since arseni- 

 cal and mercuric antisj^philitics have no effect, while it clears up in 2-3 weeks 

 on treatment with dilute nitrate of mercury ointment, although 2-3 months are 

 necessary to eradicate it completely. The incidence of the disease is from in- 

 fancy to late puberty. It tends to disappear or become less after puberty. 

 Occasionally new hair grows Avhere the crust or scutulum is removed, but 

 more often scar formation results in alopecia, in which case the condition is 

 called ''kaalkop." One boy showed no evidence of present syphilis and gave a 

 negative Wassei-mann reaction. None of the 4 cases intensively studied showed 

 any other lesions suggestive of syphilis. 



Achorion annulosum Cazalbou, Rev. Path. Comp. 14: 131-144, 3 figs., 1914. 



Bodinia annulosa Ota & Langeron, Ann. Parasitol. Hum. Comp. 1: 329, 

 1923. 



Colony brown gray greenish, glabrous with concentric rings, mycelium 

 hyaline with refringent granules, spores 3-6/a. 



Grubyella ang-olensis Brumpt, Precis Parasitol. ed. 4, 1304, 1927 ; Froilano 

 de ]\rello & Paes, Rev. Med. Angola, 505-513, 1923 ; Cong. Med. Trop. Afrique 

 Occidentale, Loanda, 1923. 



Lesions similar to Microsporum in many details, crusts lighter and less ag- 

 glomerated than in Trichophyton: on horee, France. Not inoculable into guinea 

 pig. Hair grayish. Invading mycelium 2-4/a(-5/a) in diameter, slightly 

 branched, straight or slightly sinuous, rarely septate. Spores variable in size 

 in spore sheath, up to 7/x, sometimes irregular. Fringe of Adamson in root 

 of hair. 



Chlamydospores up to 20/a, hyphae 3-4yLi, of variable diameter. Aleurospores 

 present. 



Colony in 20 days at 25° C. is 4 cm. in diameter, little elevated above me- 

 dium, surface of dark brown, smooth, concentric zones between fine, velvety, 

 greenish gray zones of equal width, center slight velvety elevation, periphery 

 of fine radiations, outer half of slight radial folds. The velvet gradually dis- 

 appears and by the thirty-fifth day colony is glabrous, moist, finely verrucose, 

 at first deep brown, then color of gingerbread. Immersed margin deep 

 orange; reverse concolorous. On Sabouraud glucose, less growth, glabrous 

 zones deep orange, velvety zones grayish, the glabrous zones giving way to 



