800 



MEDICAL MYCOLOGY 



dent relationsliijjs. Tliere are few pathogenic species, but one of them, 8. 

 Schencki and its \'ariety Beurmanni, is rather widespread and serious. 



The organism often enters through a wound, such as a prick of a thorn, 

 and produces cutaneous lesions which may or may not later become systemic. 

 The cutaneous types, in which multiple subcutaneous gummata develop with 

 or without ulceration, appear to be the most frequent type in France, while 

 lymphangitic sporotrichosis and adenitis seem to be more frequent in the 

 American literature. AVhere the disease becomes systemic, various organs 

 may be involved, such as the mucous membranes, muscles, bones, joints, very 

 rarely the testicles, epididymis, lungs, and brain. For a full recent discussion 

 of the clinical aspects of this disease, the reader is referred to the excellent 

 account in Beurmann & Gougerot, Les SporotricJioses, 1912, and Jacobson, 

 Fungous Diseases 128-145, 1932. 



Fig. 121. — Rhino claMum coprogenuni Saccardo & Marchal. ' (After MarchaL) 



The delimitation of species in this genus is very difficult. Color, which 

 has often been used not only to separate species but even genera, has been 

 shown by Davis (1915) to be variable. Practically all the strains that he 

 tried formed pigment when first isolated; carrot, potato, 3% maltose agar, and 

 3% glucose agar are more suitable media for pigment production, as is also 

 an abundance of oxygen, while light is apparently without effect. Albino 

 strains frequently occur and remain fixed even after passage through an ex- 

 perimental animal. Meyer & Aird (1915), after a study of 18 strains, found 

 some differences in carbohydrate fermentation, but these were not sufficiently 

 constant or correlated with other characters to warrant separation into spe- 

 cies. Meyer (1915), while admitting that rarely is the equine sporotrichosis 

 transmitted to man. w^as unable to find sufficient differeiiees in the strains to 

 separate them. 



