828 MEDICAL MYCOLOGY 



white velvet. On sweet potato, growth white, filamentous, becoming thicker 

 and velvety with the substrate slightly browned ; finally brick red with a new 

 layer forming which in turn becomes brick red. In glucose broth, liquid at 

 first cloudy, becoming clear with large flakes of hyphae clinging to the glass, 

 a gelatinous ring forming at the surface and becoming yellowish. 



Cephalosporium griseum Gougerot, Burnier & Duche, Bull. Soc. Frang,. 

 Derm. Syphiligr. 40: 417, 418, 1933. 



Isolated from an ulcer on the leg following puncture by piece of rusty 

 iron, abscess and ulcer formed, 4x2 cm., infiltrated, thick, margins elevated, 

 violet, surface rugose, verrncose. Wassermann negative. Lesion healed after 

 treatment with 6 gm. potassium iodide internally per day and local applica- 

 tions of tincture of iodine after 25 days. 



Hyphae 3/* in diameter, conidia elongate or ovoid, 24.3 x 5.4/x,, agglomer- 

 ated into heads. 



On Sabouraud glucose agar at 25° C, colony forms grayish tufts. 



Cephalosporium pseudofermentum Ciferri, Arch. Protistenk. 78: 227-237, 

 1 pi, 1932. 



Isolated from an atypical case of gingivitis accompanied by intestinal dis- 

 turbance, Santo Domingo. Cultures lost in the hurricane of 1930 before the 

 study of cultural characters or pathogenicity was completed. 



Mycelium repent, slender, septate at branches, 1.5-2.5^i in diameter, that 

 developing within the substrate more irregular, 2-6/x in diameter; intercalary 

 chlamydospores present and budding off occasional sprout cells which may 

 sprout further by unipolar budding. These pseudoyeast cells never form giant 

 cells, aggregations of cells, etc., as in the yeasts, and germinate directly to 

 hyphae. Probably they are only a temporary condition produced by unfavor- 

 able conditions for normal development, such as occurs in widely different 

 groups. Conidiophores 20-50/x tall; conidial heads 5-45/^, mostly 10-20/i in di- 

 ameter; conidia 1.5-2.5 x 3-5/i,. 



Colonies at first suggesting those of a pink yeast, soon showing a margin 

 of fine filaments, pale rose, old rose, or carmine. In liquid media, producing 

 a pellicle, at first arachnoid' then with rose colored islets ; little sediment of 

 yeastlike cells, dirty yellow ; conidial heads rare on liquid media. 



Cephalosporium kiliense (Gruetz) Hartmann, Derm. Woch. 82: 569, 1926.* 



Acremonium kiliense Gruetz, Derm. Woch. 80: 765-774, 1925. 



Cephalosporium asteroides griseum Gruetzii Benedek, Arch. Derm. Syphilis 

 154: 166, 1928. t 



Cephalosporium Acremonium Pollacci & Nannizzi, I Miceti Pat. Uomo 

 Anim. 9: No. 81, 1930; Pittotti, Riforma Med. 48: 1567, 1568, 1932; non Corda, 

 1839, which is a saprophyte. Cf. Benedek, Derm. Woch. 88: 892-897, 1929. 



♦Hartmann nowhere uses this combination, but he actually shows that Acremonium 

 kiliense Gruetz belongs in Cephalosporium. Apparently the lack of the formal combination was 

 an oversight. 



tBenedek describes the species in Latin in order to rename it, thinking that a descrip- 

 tion in the vernacular was invalid by the International Rules of Nomenclature, but he ovei^ 

 looked the fact that only binomial names are valid ; and by his use of a polynomial, his pro- 

 posed name was also invalid. The International Congress at Cambridge 1930 validated all 

 names of species described in vulgar languages from 1908 to 1932. 



