826 MEDICAL MYCOLOGY 



Sterile hyphae hyaline, septate, about 4.5/i in diameter; fertile hyphae more 

 slender 1.5-2.5/x in diameter, simple or branched; conidia in heads, oblong or 

 ovoid, often curved, 4-18ya long, vevy rarely septate, hyaline; chlamydospores 

 intercalary, often in chains of 2-3 cells. 



On Sabouraud and on Pollacci agar at 25° C. colonies with floccose center 

 and zones of alternating light and dark chestnut. On leather, colony thin, 

 white, becoming clear chestnut. On hair, colony thin, white. On feathers, 

 colonies small white, more or less discrete. On blood agar and coagulated 

 serum, colony thick and yellow. On potato and carrot, colony spreading, 

 white, powdery, the pellicle over the liquid becoming rose color on the carrot. 

 On Raulin liquid, milk and glucose broth, pellicle thick, gelatinous, white, be- 

 coming chestnut spotted or finally chestnut. No fermentation, milk coagu- 

 lated. Optimum temperature about 25°, maximum about 35° C. 



CEPHALOSPORIUM 



C ephalosporium Corda, Icon. Fung. 3: 11, 1839. 



The type species is C ephalosporium Acremonmm Corda (Fig. 127). 



Hyphae repent, conidiophores unbranched, developing as short lateral 

 branches, erect, not swollen at the tips. Conidia arising singly at the tips, 

 being pushed aside by the following conidium and clinging together by a thin 

 layer of gel on the conidial Avail, until a more or less spherical mass of conidia 

 is formed. 



It seems quite likely that the mechanism of conidial formation in this 

 group is very close to that of Aspergillus and Tenicillium, but the conidiophore 

 is not swollen or flask-shaped, and if the spores are essentially in chains, they 

 slip past each other so soon that they form spore balls, as in Gliocladium. This 

 group is in need of intensive study to clarify its position. 



Several species have been reported as pathogenic, but the group is mostly 

 saprophytic and reports should be scrutinized with extreme care to see that 

 pathogenicity is proved. They are very frequently found as contaminants in 

 laboratory cultures. 



Key to Species 



Conidiophore simple. 



Conidia elongate (3 or more times as long as broad). 



Conidia 4 x 1/x, colony white, becoming rose color; saprophyte. 



C. Acremonium,. 

 Conidia 6 x 2ai, colony with brown center and white margin. 



C. Boulcourei. 

 Conidia 24.3 x 5.4ytt, colony grayish. C. griseum. 



Conidia ovoid, not more than twice as long as broad. 



Colony white, then rose color, conidia 3-5 x 1.5-2.5^; gelatin probably not liquefied. 



C. pseudofermentum. 

 Colony grayish, sometimes becoming greenish ocliraceous. 



Conidia 3 X 1.5^; gelatin not liquefied. C. Mliense. 



Conidia 10-12 X 5-6^. C. Boydii. 



Colony remaining white, conidia 5.2 x 2.6//, gelatin liquefied. 



C. niveolanosum. 



