450 



E. WACE CARLIER 



Appearances présentée by the liver cells 3J4 hour after smellingfood, 



FIG. 14. 



The cell outlines are difficult to distinguish, the cytoplasm is very 

 pale and open, though not distinctly vacuolated; its spherules are not 

 conspicuous and it has lost the peculiar blistered appearance noted in the 

 half hour spécimens. The structureless material is abundant in sonne cells 

 and arranged in big masses, in others it is very scanty or altogether absent. 



The nuclei of .ail the cells are very pale and wrinkled with large 

 nucleoli, many of which are migrating. The small cells surrounding the 

 portai tracts are similar to those of the preceeding spécimens, but their 

 nuclei are rather more clouded ; the capillaries are rather narrow. 



Appearances presented by the liver cells i hour after smelling food, 



FIG. 15. 



The cell outlines are not distinguishable, the cytoplasm is very pale, 

 less open, without vacuoles and consists of numerous fairly crowded 

 spherules, which are rather large in those cells the nuclei of which are 

 beginning to cloud, i. e. in the outer zone cells. The nuclei of the cells of 

 the outer zone are swollen, exhibit an early stage of clouding and contain 

 small nucleoli. The cells of the middle and inner zones are in much the 

 same condition as previously; the small cells round the portai tracts are 

 not more deeply stained than the others and their nuclei are beginning to 

 clear. The capillaries are narrow. 



Appearances presented by the liver cells i 1/4 hour s after smelling food, 



FIG. 16. 



The cell outlines are again just visible, the cytoplasm is rather more 

 pink in tint than previously and consists of larger spherules less closely 

 packed together ; some vacuolation is beginning to occur and the structure- 

 less material is in greater amount and clustered. The nuclei are ail clouded 

 except those of the small cells surrounding the portai tracts which hâve 

 become almost cleared up ; the capillaries are not dilated. 



Appearances presented by the liver cells 1 ih hour after smellingfood, 

 FIG. 17. 



The cell outlines are now distinct, the cytoplasm that consists of 

 smaller spherules is becoming distinctly vacuolated and contains an 



