5i4 ANNALES DE LINSTITUT PASTEUR 



in some cases at least , Ihey arc (riie cliromidia. 1 may men- 

 tion here Ihal 1 drew atlenlion to extrusion of grains from the 

 nucleus in my memoir (1909, p. 795 and p. 802) on Trypanosoma 

 lewisi. 



Stimmanj and Conchisions. — Tiiis brief note does not a 

 bring forward any facts hitherto unknown, but attempts to 

 compaie and coordinate certain known facts with a view to 

 demonstrate Iheir essential similarity and homology. The 

 conclusion reached is that the phrase <( infective granule » is 

 misleading and erroneous, since the bodies so termed are 

 true endogenous chromidial buds. Consequently the term 

 « granule-formation » should be replaced by « endogenous 

 bud-tormalion » and the term « granule shedding » by extru- 

 sion of buds or some similar phiase. 



Lister Institute, April, 1914. 



REFERENCES 



Balfoub, A. (I9H). — Tlie Infeclivc Granule in certain Protozoal Infections, 

 as illustrated by the Spirocha'tosis of Sudanese Fowls. British Medical 

 Jourjiai, 1911 (1), p. 752 (April 1st). v 



Fry, W. B. (1911). — A Preliminary Note on the Extrusion of Granules by 

 Trypanosomes. Proc. Roy. Soc. (B) lxxxiv, p. 79, 80, 1 text-fig. 



FiiY, W. B. and Ranken, H. S. (1913). — Further Researches on the Extrusion 

 of Granules by Trypanosomes and their Further Development. /'?'oe. 

 Roy. Soc. (B) Lxxxvi, p. 3'n-.393, pis. ix-xi. 



Henrv, H. (1913). — The Granule Shedding of Uœmoqregarina simondi. A con- 

 sideration of the Infective Granule in the Life-history of Protist Orga- 

 nisms. Journ. Pathol. Bacterial., xvui, p. 240-258, pis. xx-xxii. 



Liston, W. G. and Martin, C. H. (1911). — Contributions to the Study of 

 Pathogenic Amœbœ from Bombay. Quart. Journ. Micr. Sci., lvii, 

 p. 107-128, pis. xvi-xviii. 



MiNCHiN, E. A. (1909), — The Structure of Trypanosoma levisi in Relation to 

 Microscopical Technique. Quart. Journ. Micr. Sci., lui, p. 755-808, 



pis. XXI-XXIII. 



— (1912). — An Introduction to the Study of the Protozoa. London 

 (Edward Arnold). 

 Popoi'F, M. (1911). — Ueber den Entwicklungscyclus von Amorba minuta. 

 Arch. Protisienkunde, xxii, p. 197-223, j)ls. xiii, xiv, 7 text-fig. 



