RUBIACEAE 
Isertia rosea Spruce in Martius, Fl. Bras. 6, pt. 6 (1889) 284. 
CoLomBIiA: Comisaria del Vaupés, Rio Kananari, Cachivera de Palito. 
July 25, 1951. R.E. Schultes et 1. Cabrera 13148. 
The Taiwano Indians of the Rio Kananari value a decoction 
prepared from the leaves of this plant as an effective febrifuge. 
It is taken hot in quantity every several hours to reduce fever 
by stimulating perspiration. 
Pagamea coriacea Spruce ex Bentham in Journ. Linn. Soc. | 
(1857) 110. 
CoLoMBIA: Comisaria del Vaupés, Rio Apaporis, Raudal de Jerijerimo. 
March, 1951. R.E. Schultes 12108. — Same locality. June 13, 1951, R.E. 
Schultes et 1. Cabrera 12467; January 21, 1952, R.E. Schultes et 1. Cabrera 
14953; March 15, 1952, R.E. Schultes et I. Cabrera 1593]. — Rio Karuru, 
Mesa de Yambi, Savannah Goo-ran-hoo-da’, April 15-16, 1953, R.E. 
Schultes et 1. Cabrera 19169. 
The Indians in the region of Raudal de Jerijerimo on the Rio 
Apaporis value this plant as a very efficaceous remedy for 
reestablishment of the ability to walk following attacks which, 
in age, appear to deprive Indians from free use of the legs. The 
causes of this curious disease (which is not uncommon) are 
unknown. 
The bark of the young branches is scraped and, in the fresh 
condition, is boiled into a decoction, which must be drunk over 
a period of two or three weeks. Administration of this tea is 
reputed to result in strong stimulation of the afflicted patient 
and sometimes in ability to regain use of the legs. 
Pagamea macrophylla Spruce ex Bentham in Journ. Linn. 
Soc. 1 (1857) 110. 
CoLomBIA: Comisaria del Vaupés, Rio Piraparana, Cano Paca. Septem- 
ber 18, 1952. R.E. Schultes et I. Cabrera 17581. 
The leaves of Pagamea macrophylla are sought by medicine 
men of the Makuna tribe. They are dried, pulverized and aspi- 
rated as a powder during diviniation ceremonies. There is no 
indication, however, that they have hallucinogenic properties. 
The Maku name of this plant in the Rio Piraparana is ma-ha- 
shu'-ke-ma. 
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