with the rising concentrations of cocaine in the blood. The 
shape of the curves fits with the subjective effects reported. 
The differences in stimulation between using whole coca 
leaves or coca powder and taking cocaine by local application 
in the nose or by intravenous injections seems to be essentially 
a difference in means of administration and dosage. There is, 
consequently, no reason to believe that the stimulating effect 
achieved by the use of either coca leaves or powder is not due 
to cocaine. 
An extended report on this experimental project, of which 
the present article is an abstract, will be published in the 
Journal of Ethnopharmacology. 
The research upon which this abstract is based was carried 
out under NSF Grant No. DEV 72-02536-Garey 6-446406- 
21412. 
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