Psychotomimetic effects are unknown for ergometrine, 
which is used to a large extent in obstetrics as a utero- 
tonic and hemostatic agent. When using the small dos- 
ages which are administered for this purpose, the alkaloid 
apparently has no action on the psychic functions. Its 
occurrence in the alkaloid mixture of Ipomoea violacea 
can thus have no significant effect on the action of badoh 
negro. Furthermore, chanoclavine, which has no out- 
standing pharmacological activity, appears to play no 
part in the occurrence of the psychic effects of badoh and 
badoh negro. 
According to the results of experiments performed 
thus far with pure alkaloids, it appears as though d- 
lysergic acid amide, elymoclavine and lysergol and pos- 
sibly also d-isolysergic acid amide are mainly responsible 
for the psychic effect of ololiuhqui. 
Systematic comparative investigations are presently 
being performed with the pure alkaloidal principles of 
ololiuhqui and total extracts from the seeds so as to as- 
certain the psychic effect on humans. These will show 
whether the alkaloids described alone are responsible tor 
the psychotomimetic effects, which, in view of our pres- 
ent knowledge, seems probable, or whether other factors 
play a part. 
[ 210 ] 
