12 



Chittende7i and Lambert — Experiments on the 



Experiment V. 



Gray and white buck. This experiment was a repetition of No. 

 IV, the same amounts of uranium salt being given and at the same 

 intervals of time. The animal died three days after the last dose of 

 uranium had been administered. The symptoms were not very 

 marked, simply loss of muscular power, and a gradual wasting away. 

 On post mortem, the heart was found in diastole and engorged with 

 blood. Lungs congested. The liver was black with the blood in it, 

 especially on the edges, and when pressed between the fingers was 

 extremely pliable and of a soft, pulpy consistency, showing marked 

 parenchymatous degeneration. The gall bladder was distended with 

 very dark bile. Both kidneys had non-adherent capsules. The left 

 kidney was slightly congested. The intestines had an inflamed patch 

 in the jejunum and were congested for a foot above it. The bladder 

 contained a little urine, which gave reactions for both sugar and 

 albumin. Sugar and albumin were also found in the urine several 

 days before death. 



Experiment VI. 



In this experiment still smaller amounts of uranium were adminis- 

 tered, a total of only 0-175 gram being given in three days. The 

 foUowino; table shows the dosase and tlie chanoes in the urine : 



There were no noticeable symptoms of toxic action aside from the 

 changes in the urine, and even here there was no sugar at any time 

 present. Just as the albumin had almost disappeared from the urine 

 and we looked for speedy recovery, the animal Avas found dead (on 

 the 23d). Post-mortem showed the heart in diastole, engorged with 

 blood. Lungs normal. Liver normal, aside from a slight congestion. 



