154 



a. H. Chittenden and C. JVbrris — The Relative 



Experiment V, with nickel. 

 In this experiment, 1-8 grams of nickel nitrate were grven by 

 mouth during five days to a rabbit ofr5 kilos, weight, the individual 

 doses being of about the same size as in preceding experiments. On 

 the sixth day, the animal died of heart failure. Following is the 

 distribution of the poison. 



Total weight Ni per 100 grams 



of organ. Weiglit of Ni. of tissue. 



grams. milligrams. milligrams. 



Stomach and contents 73-00 3-2 4-38 



Small intestines 59-10 1-8 3-04 



Large intestines 36-40 9-9 27-20 



Caecum 176-00 36-5+ 20-74 + 



Liver.-. 58-00 8-1 13-96 



Kidneys '. 10-27 0-8 7-79 



Heart 7-42 1-3 16-63 



Lungs. 6-52 0-2 3-06 



Muscle of legs 97-30 2-6 2-67 



Muscle of back 35-00 3-7 10-'57 



Experiment VJ, with cobalt. 



In this experiment, an attempt was made to ascertain something- 

 regarding the elimination of the cobalt through the kidneys. For 

 this purpose, the urine was collected each day and the cobalt deter- 

 mined by the same method as used in the analysis of the organs. 

 The rabbit (body weight 2-5 kilos.) was dosed as follows : 



Nov, 



Dec. 



Examination of the 2^ hours' urine. 

 30 c.c. contained 1-3 milligrams Co. 

 50 " " 6-1 



73 



120 



6- 



23-3 



