,j2 E. WACE CARLIER 



The nucleoli are sometimes large and often situated near the margin of 

 the nucleus, a few may still be seen in process of éjection. 



Near the pyloric end the nuclei are rather lilac coloured than blue, 

 owing to the lanthanin granules exhibiting an affinity for the acid as well as 

 for the basic dye, which indicates that their nature is becoming modified. 

 Nucleolar extrusion is going on apace. We hâve hère probably a further 

 stage of nuclear repair, Plate III, fig. 4. 



U4 Hoiirs afterfood. — Plate I, fig. 6. 



The stomachs of thèse animais were quite empty when opened, but the 

 intestines were filled with digested worm. 



The gland lumen is small, the cells lining it are large and filled with 

 brightly stained zymogen granules that vary considerably in size; the larger 

 ones being usually situated in the neighbourhood of the nuclei. The granules 

 average 1,4— 1,6 v- in diameter. The protoplasm which is hardly visible 

 owing to the multitude of granules it contains, stains of a pale blue colour, 

 of the same tint as in the fasting animal. 



The nuclei are plump-looking and measure on an average 12,57 X 

 13,18 1^ they are therefore bigger than thèse of the previous section. They 

 also exceed in size thèse of the newt that had long fasted and are less an- 

 gular. Many of thèse nuclei contain great numbers of tiny lanthanin gra- 

 nules that stain of a beautiful lilac tint, but though very numerous they 

 no longer obscure the other éléments. They are in a similar, but more 

 advanced condition than thèse of the pyloric end in the last préparation. 



The chromatin is not very abundant, though more so than in the pre- 

 ceding case, it is arranged in elongated masses and streaks, that are more 

 or less united together by fine threads of chromatin, i. e. the karyosomes 

 hâve no longer that isolated appearance so conspicuous in previous cases. 



In other cases and this applies to almost every nucleus near the pyloric 

 end, the lanthanin granules are less numerous, larger, and stain of the 

 same sky-blue tint as described in the case of the fasting animal. The chro- 

 matin is still more abundant in thèse nuclei and stains deep blue. Plate III, 



FIG. 5. 



The nucleoli are large and often numerous, but their extrusion appears 



to hâve ceased. 



The cells seem now to hâve entirely recovered from their exertions 

 and are again ready as soon as called upon to recommence secreting. The 

 newts themselves exhibited every sign of hunger, hunting about the vessels 



