414 



E. WACE CARLIER 



of dividing by the call for sécrétion, other bave only just begun to divide 

 and are still in the wreath stage. 



Near the pyloric end the cells contain much smaller granules than at the 

 cardiac end and few gland acini show any signs of secretory activity. Hère 

 also some cells may be seen in ail stages of mitosis. 



1 How a/ter food. — Plate I, fig. 8. 



The gland acini again vary considerably in appearance ail not being in 

 the same stage of sécrétion. In most of them the lumen has now become of 

 considérable size, owing to further diminution in the size of the cells, they 

 also contain fewer zymogen granules which vary in size from i ,56 to 0,5 \>- in 

 diameter, the smaller ones not staining at ail deeply. 



The protoplasm is somewhat ragged looking owing to vacuoles présent 

 in it and blue grey in colour, the cell envelopes are pale blue. Instead of 

 each zymogen granule lying in a separate space in the protoplasm as during 

 rest, several granules may be seen lying in the same space, which is much 

 larger than before. 



The nuclei appear somewhat wrinkled and measure 10,19 X i2,44 i-"- on 

 the average. They do not contain very much chromatin, but that présent is 

 arrangée! in somewhat large karyosomes which hâve a washed out or water 

 logged appearance and stain of a watery blue. They are not so stellate as in 

 the previous spécimen and measure on the average some 2,16 \i. in diameter. 

 The remainder of the chromatin is arranged against the nuclear wall and 

 gives it a thickened appearance. The lanthanin granules are not numerous, 

 being often greatly reduced in number and stain of a slaty violet colour. 



A few nuclei exhibit somewhat unusual shapes some being triangular, 

 others presenting latéral projections in onc or other direction, Plate III, 

 FIG. 7. 



The nucleoli are usually of moderate size and deep venons red in co- 

 lour, some are passing through the nuclear wall into the protoplasm. 



Some cells in thèse préparations are just beginning to secrète and their 

 nuclei when measured were found to be of considérable size, namely 1 1 ,29 |a 

 X iSj-'^S !'■ showing that at a very early stage, the nuclei increase somewhat 

 in size. 



In this case no mitosis was observed in the oxyntic cells. 



Near the pyloric end the oxyntic cells contain numerous zymogen gra- 

 nules that are very small, almost like dust in some cases. Few cells show 

 active secretory changes and no mitosis was observed. 



