THE NEWTS STOMACH DURING DIGESTION 4I5 



1 1/2 Hoiirs after food. — Plate I, fig. 9. 



The gland lumen is still larger and the cells further reduced in size. In 

 some cells the zymogen granules are absent from the neighbourhood of the 

 nuclei and in a few from the basai half, giving a two zoned appearance. The 

 granules are mostly of médium size, though some large ones are présent, 

 measuring on an average 2 \'. across, but by far the most numerous do not ex- 

 ceed 7 i-"- in diameter. The protoplasm is in small amount vacuolated and of 

 a pale grey colour, the cell envelopes are well seen and pale blue. In some 

 cases the gaps between the cells extend to within 4 :'• of their attached ends. 

 The gaps are wide and cuneiform on section with somewhat blunted apices, 

 which point towards the connective tissue outside the glands. 



The nuclei are very irregular in shape with wrinkled envelopes and 

 présent at times projections suggestive of amaeboid movements. The nuclear 

 envelopes are thickened by small masses of chromatin applied at intervais 

 against their inner surfaces. 



The remainder of the chromatin is arranged in isolated rounded karyo- 

 somes, which are not abundant and stain of a blue colour of moderate in- 

 tensity. The lanthanin granules are further diminished in number and of a 

 pale blue grey colour. The nuclei measure on the average 10,75 !-^ X 10,09 v- 



The nucleoli are irregular in shape, often of large size and stain deep 

 venous red. They may be seen in the process of extrusion in some cells. Mi- 

 totic figures are visible hère and there. 



Near the pyloric end the process of excrétion is not so far advanced, but 

 the zymogen granules are larger than in the preceding préparation. Nucleoli 

 are présent in process of extrusion and some mitosis is occurring. 



2 1/2 Hours after food. — Plate I, fig. 10. 



The gland lumen is of about the same size as in the last spécimen and 

 the cells are shrunken and contain fewer zymogen granules which are of 

 médium size; averaging i ,3 |j- in diameter. Owing to their diminution in num- 

 ber and to the decrease in size of the cells the protoplasm is somewhat more 

 visible and stains ofa pale grey colour; the cell envelopes show no change. 



The nuclei are smaller, very irregular in outline and average 9,75 \i. X 

 10,95 fj. in size. The chromatin is not abundant, the small rounded karyoso- 

 mes of which some are adhèrent to the inner surface of the nuclear mem- 

 brane, stain blue and are often very scanty. The lanthanin granules are 

 scanty and ofa pale grey colour. 



