THE NEWTS STOMACH DURING DIGESTION 41? 



The nuclei which are very irregular measure 8,8 ;j- X 1 1 ,8 a and contain 

 but little chromatin. The kar)'osomcs are usually sinall and shrunken, they 

 however stain of a blue colour and may be seen adhering to the inner sur- 

 face of the nuclear membrane giving it an irregular appearance. The lan- 

 thanin granules are few in number and stain pale blue so that the nuclei 

 appear very colourless. At this stage the nuclear juice contains very little 

 coagulable material, Plate III, fig. 9. 



The nucleoli are as a rule not numerous and for the most part of mé- 

 dium or small size, a few large ones may be seen which appear to stain 

 less intensly than the smaller ones and a few of thèse are being extruded. 

 No cells in process of division were observed. 



Near the oesophageal opening the cells are much less shrunken and 

 the gland lumina smaller. There are plenty of zymogen granules in thèse 

 cells which are of somewhat large size m.easuring some 2,6 i-^ in diameter 

 a good many smaller ones i ,7 ,j. are présent as are a few below 1 [j. in diameter. 

 The protoplasm stains pale blue; it is not abundant except hère and there 

 near the base of some cells where it appears condensed somewhat. The 

 cell envelopes are difficult to distinguish owing to the zymogen granules 

 coming close up to them. The nuclei are plump looking and of a somewhat 

 dark blue colour owing to the présence of numerous lanthanin granules. 

 The nuclei measure 12,55 X 15,83 ;j. but contain no great abundance of chro- 

 matin of which little is spread out under the nuclear envelope. It is gathered 

 into small karyosomes that stain deep blue or reddish blue. In some the 

 chromatin is more abundant than in others, but in ail cases there is always 

 a reddish tint underlying the deep blue. The cells no doubt hâve already 

 begun to repair their used up substances. 



It would seem from this that at the fourth hour the activity of the cells 

 in the middle part of the stomach is at its height, whilst near the œso- 

 phagus, where the changes are first observable after ingestion of food, 

 that the maximum is reached correspondingly earlier than elsewhere in 

 the stomach and that repair sets in hère also somewhat sooner than else- 

 where. 



Near the pyloric end on the other hand, the cells are shrunken and the 

 lumina wide, few zymogen granules being présent. The nuclei are shriveled 

 and contain a red staining almost diffluent looking chromatin. The lanthanin 

 granules are pale grey. This corresponds with the condition described in 

 the middle of the stomach in the previous spécimens and marks a less 



