, , Q E "WACE CARLIER 



4 1 o 



advanced stage in thèse cells, showing that the changes induced by the 

 présence of food in the stomach are manifested at the pyloric end nearly an 

 hour later than in the middle of the organ and about two hours later than 

 in the glands near the œsophageal junction. 



5 Hours a/ter food. — Plate II, fig. 14 and 15. 



The lumen is now somewhat smaller owing to a slight increase in the 

 size of the cells which contain more zymogen granules of médium or small 

 size that do not stain readily. The protoplasm is pale blue and easily seen. 



The nuclei are less wrinkled n ,22 ,.. x M,2 5 ^^ and somewhat dusky in 

 appearance owing to increase in the number of lanthanin granules. Thèse 

 are of small size and stain deeply blue. The chromatin that stams blue 

 does not appear increased in quantity though small karyosomes somewhat 

 larger in size than lanthanin granules are visible in fair number and can be 

 recognised by their deeper blue colour. Extrusion of nucleoli appears to 

 hâve'' now ceased as lias also cell division, Plate III, fig. 10. 



At the pyloric end the cells are still very much reduced in size and the 

 crranules still fewer in number. But the karyosomes are no longer stained of 

 a distinct red, being more of a purple colour than in the last spécimen, 



though still spread out. 



(There is a remarkable number of eosinophilous cells in this préparation 



in the connective tissue and lymph spaces). 



6 Hours af ter food. — Plate II, fig. 16. 



The lumen is still narrower and the cells more protruding. They con- 

 tain numerous zymogen granules of large size, very few small ones being 

 présent. The protoplasm stains pale blue and is difficult to see owmg to 

 the number of granules it contains, the cell wall is also pale blue. 



The nuclei are less angular than previously and stain deeply owing to 

 the large number of lanthanin granules which fill them. There is however no 

 crowding of the lanthanin granules and therefore no cloudy appearance In 

 colour they are deep slaty blue with a decided tendency to lilac. The chro- 

 matin is more abundant than in the previous spécimens and the karyosomes 

 tend to become united into stars and figures of irregular shape (boyau). 

 They stain deep blue. The nuclear envelope is also blue but has only a few 

 small masses of chromatin adhèrent to it. The nuclei measure on an average 

 1 1 ,44 X 14,55 i^-- That is to say they hâve increased m size. 



