432 E. WACE CARLIER 



size. The protoplasm between the cups and thc nuclei measures 4,3 i>- in 

 length and is filled with tiny red granules. 



The nuclei appcar large and fill thc cells laterally, they measure 22,98 

 X 6,6 [>■. The nuclear membrane stains blue and has some chromatin ad- 

 hèrent to it. The chromatin is fairly abundant, arranged in dots and dashes 

 and is dark blue in colour. The lanthanin granules are pale blue and not 

 crowded. The nucleoli are small and their extrusion appearsto hâve ceased. 

 Below the nucleus the protoplasm is pale blue and longitudinally striated 

 with minute vacuoles in abundance. Total length of cells 56,6 i-^, the peri- 

 cellular lymphspaces are fairly wide. 



Over the pyloric glands the mucigen cups measure 7,3 ;^ in length and 

 are convex at both extremities. 



The red granule zone measures 3,6 :>■ or less in height and is packed 

 with granules. The nuclei which are rather rich in chromatin measure 

 20,5 X 7,36 i-"- and the cells measure 46,6 i^- in total length. 



The experiments of the lirst séries seem to show that when sécrétion 

 commences, thc mucigen cups of the surface cells first diminish in size, to 

 rapidly increase in dimension till they reach their maximum size about 

 the 68"' hour after food. (Langlev "^ says that the}^ increase in size during 

 digestion). Subsequently they again diminish and regain their normal 

 volume about 1 14 hours after food. 



Sécrétion also produces rapid diminution of the red staining granules 

 below the mucigen cups and the approximation of the nucleus to the inner 

 ends of the cups which tend to become inverted; after repair sets in the nu- 

 cleus again withdraws irom the cup and finally new red granules again 

 make their appearance in the pi^otoplasm between them. The reappearance 

 of the granules is however a late occurence in the process of repair. 



During repair the cells also tend to increase in size to some extent, 

 becoming turgid and more closely approximated, so that the pericellular 

 lymph spaces appear diminished or almost obliterated; later on the cells 

 again regain their usual resting dimensions and the lymph spaces reappear 

 of normal width. With regard to the nuclei they appear to diminish in vo- 

 lume, rather than in length which may indeed at one time be somewhat 

 increased, the diminution is especially marked in the transverse diameter. 



