THE NEWTS STOMACH DURING DIGESTION 4 33 



They become shrivelled, cloudy and exhibit the other changes observed 

 and described in the case of the oxyntic cells. The nucleoli also undergo a 

 similar gamut of changes ending in extrusion from the nuclei as described 

 above, except that they do not appear to acquire such large dimensions pre- 

 vious to expulsion probably owing to a greater intolérance of the nuclei of 

 thèse cells to the accumulation of effete material. 



SECOND SERIES OF EXPERIMENTS. 



1/2 Hour afterfood. 



At the œsophageal end of the stomach the mucigen cups of the surface 

 cells are large and convex externally, they appear to bulge considerably 

 beyond the cément ring. The sides are cylindrical but the cups are concave 

 internally. Many mucigen granules of a pale blue colour are présent, but 

 there is no crowding. They measure rJ,55 X 10,49 [>■. 



The protoplasm between the nucleus and the lower end of the cup is 

 reduced to a minimum and contains no red staining granules. 



The nucleus which appears short in most cases projects up into the 

 hollow of the mucigen cups and measures 14,9 x ^^^ \>-i it is somewhat 

 wrinkled. The nuclear membrane stains of a dusky blue tint, the nuclei 

 themselves staining dark lilac. The chromatin which is scanty and mostly 

 arranged in small karyosomes that are separated from each other, stains of 

 a dusky blue. The nucleoli are small and usually multiple. Some nuclei 

 are less clouded, with fewer deep violet grey lanthanin granules. 



The inner ends of the cells are violet grey and présent many small va- 

 cuoles. The cells measure in total length 32,16 [>■. The peri-cellular lymph 

 spaces are fairly wide and many leucocytes, some in process of division, 

 may be seen migrating between the epithelial cells. 



Near the pyloric end the mucigen cups are longer than they are broad 

 measuring 12,05 x iOi'5 i^; their outer extremities are convex but do not 

 project much beyond the cément net, their inner extremities are flattened 

 or slightly concave, they contain numerous but not crowded pale blue zymo- 

 geri granules. Red staining granules are présent hère in the narrow zone 

 of protoplasm between the nucleus and the inner end of the cup. The nu- 

 cleus fills the cell laterally, but is somewhat short and apparently slightly 

 wrinkled. The nuclear envelope and the chromatin stain alike of a dusky 



