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E. \VACE CARLIER 



removed as the oxyntic granules often are, and that during sécrétion the mu- 

 cigen cups appear to increase in size somewhat and to afterwards diminish, 

 before exhaustion of the cells occurs. Asbefore, thenuclei become shrivelled 

 and cloudy and nucleoli are extruded. Repair seems to begin in the proto- 

 plasm as indicated by its reaction and increase in breadth of the cells 

 whereby the lymph spaces between them are greatly encroached upon and 

 even almost obliterated. This is followed by repair of the nucleus and finally 

 by reaccumulation of granules both in the mucigen cups and in the proto- 

 plasm beneath the cups. A remarkable fact is the rapidity with which thèse 

 red granules disappear at the onset of activity, and their tardy reproduction 

 is also worthy of note, The changes undergone by the nuclear chromatin 

 are identical with those of the oxyntic cell nuclei and will be discussed 

 along with other matters in the gênerai conclusions. 



Cells lining Ihe necks of the Oxyntic Glands and fundus of the Pyloric Glands, 



In the oxyntic glands, between the oxyntic cells and the duct proper, 

 there is a short neck lined by mucin forming cells that dififer in several res- 

 pects from those lining the ducts and surface of the stomach, but which pass 

 by graduai transition into them. In the pyloric glands, which in this animal 

 are lined by mucin forming cells only, the fundus cells are exactly the samç 

 as those lining the necks of the oxyntic glands. One description therefore 

 will serve for both. 



The cells are columnar in shape and caracterised by their short mucigen 

 cups and sessile appearance; the large oval nucleus extends down quite to 

 the attached end of the cell and between it and the mucigen cup is a broad 

 zone of protoplasm packed in the resting condition with tiny red staining 

 granules of zymogen as in the surface cells. 



The nucleus is so large that it quite fills the cell laterally and occupies 

 at least half its entire length, it has a thin envelope and is very rich in 

 chromatin as compared with other cells of the stomach. The chromatin 

 stains deeply blue and is arranged in streaks, dots and dashes united 

 by very fine strands. Lanthanin is usually fairly abundant and blue in 

 colour producing a well filled appearance in the nuclei. Nucleoli are pré- 

 sent to the number of two or three, are of small size and deep red colour. 

 The attached ends of the cells do not taper to any extent though there are 



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