158 I. I.TIMA AND K. MUE AT A 



pntient of Scheube was infected presamably in Kiashiii (see Lt.). Of 

 the six cases mentioned by us, two occared at Kyoto and the rest at 

 Osaka, Kanazawa, Tovama and Province Echio-o respectively. This 

 justifies us in believing that the parasite has a very wide distribution 

 throu2fhout the whole country. We inav further rssmue tliat special 

 research in this direction would show th.'it the parasite is by no means 

 so rare as it seems to be. 



According to Prof. Leuckart the real seat of the worm is the 

 connective-tissue as was found in Manson's case. This is fully borne 

 out by the case in which the worm was found in the subcutaneous 

 tissue (Case W) and also by the two cases in which it was located 

 evidently in the connective-tissue space around the_^ eye-bulb (Cases 

 \\ & Y.) 



Leuckart made it highly ))robable that the worm has the power 

 of changing its position — of moving through tissues to a certain 

 extent. Three of the cases just mentioned put this beyond doubt. In 

 two cases (I\' k A^) namely, the Avorm was found \c have pierced the 

 conjunctiva and to protrude itself and in one case (VI), the periodical 

 swelling of the thigh, evidently caused by the presence of one and 

 the same worm, was found to vary in position almost everytime it 

 appeared, bet-ween the part just above the knee on tlie inner sirlo and 

 the Scarpa's triangle. It Avas moreover observed that the swelling 

 changed its position of its own account during its existence. 



finder such circumstances, Leuckart's exjilanation of the exit of 

 the worm from urethra, that it had secondarily bored its way into the 

 urinary apparatus, requires no additional evidence to pnn^e its 

 correctness. 



All the known cases, except the two in which the parasite was 

 found in the orbit, tend to show that it is mostly located in the 

 lumbar or the ]ielvic region. The entrance into the urinary organ 



