THE GENUS NOCARDIA I'.i 



cream-colored in the stab. Surface colony Oxygen: Grows aerobically. Grows also 



raised, folded, pale yellow. \'o liquefaction, under anaerobic conditions. 



Milk: Small cream-colored granules along Acid production: Acid produced in serum 

 the tube. No proteolytic action. agar media, with glucose and salicin, some- 

 Starch: Hydrolyzed. times with maltose and lacto.-e. 

 Cellulose: Not utilized. Habitat: Parasite inhabiting nasopharynx 

 Nutrient broth: Good growth; volumi- of rats. Isolated from body of patienl bitten 

 nous, flaky, whitish sediment; broth clear. by a rat. 



Nitrate reduction: Negative. Remarks: Similar organisms by a variety 



Sucrose: Inverted. of names, such as .1. putorii, were also 



Source: Fermented beets. listed. Above description based on data of 



Remarks: Sodium nitrate, ammonium Topley and Wilson (1946). 



phosphate, and asparagine are utilized, al- 37. Nocardia nigra (Krassilnikov, 1941) 



though these are interior to peptone as Waksman (not A', nigra Castellani and 



sources of nitrogen. CI, aimer.- not Streptothrix nigra Rossi- 



36. Nocardia maris (Schottmuller, 1914) Doria.) (Krassilnikov, X. A. Actinomy- 



de Melloand Pais, L918 (de Mello and Pais, cetales. Izvest. Akad. Nauk. SSSR, Moskau, 



Arq. Hig. Pat. Exot. 6: IS:!, L918). 1!,ll >- 



Synonyms: Streptothrix muris-ratti Schott- Morphology: Growth rough, folded, shiny, 



miiller, L914. Streptobacillus moniliformis dough-like consistency. Cells thread-like, 



Levaditi, L925. Actinomyces muris Topley breaking up readily into rods 2 to 10 by 



and Wilson, l!)4(i. Proactinomyces muris () ~ m and cocci, 0.6 to 0.8 m- No aerial 



Krassilnikov, L941. mycelium. Gram-positive, not acid-fast. 



Morphology: Slender branching filaments, ^S ar media: Growth poor, at first color- 



0.4 to ().(i n in diameter, breaking up into less or brownish, gradually becoming darker, 



rods and cocci. Often cells form long chains later dark brown and even black. Pigmenl 



of bead-like cells, with terminal club-like " ()1 excreted in medium. Many cells are 



swellings. Nonacid-fast. swollen to :; M in diameter. 



Growth: None on ordinary media. Growth Potato: Growth good. 



occurs in presence of serum, ascitic fluid or Gelatin: No growth. No liquefaction, 



blood. Milk: No change. 



N . . • . x> ,, Cellulose: No growth. 



Nutrient agar: No growth. _ , 6 



,,, x - , Paraffin and wax : No growth. 



( ducose agar: No growth. ., , . , ,. 



,, . . . Nutrient broth: Small sediment produced, 



berum agar: Grayish-yellow, clear col- . f j- , 



• .Medium clear. 



,,m, ' s < (K2 t0 ° 3 mm m diameter, with ( , ;n . ))()ii ulilizall()n: niliz( , s glucose ;m( , 



smooth, glistening surface and entire edge. mannosej with formation of acid. 



Easily emulsifiable. Source: Seldom found in soil. 



Gelatin: No growth. Remarks: Culture rapidly loses its vi- 



Potato: No growth. ability on continued cultivation. 



Mllk: No effect - 38. Nocardia opaca (den Dooren de Jong, 



Nitrate reduction: None. 11)27) Waksman and Henrici, 1948 (den 



Blood agar: Like serum agar. No he- Dooren de .long. I.. E. Centr. Bakteriol. 



molysis. Parasitenk. Abt. II, 71: 216, L927; Jensen, 



Egg medium: Similar to growth on serum II. L. Proc. Linnean Soc. N. S. Wales 57: 



agar. No liquefaction. 369, 1932). 



