SECRETARY'S REPORT 167 



adults, have the typical seizures of this malady periodically but act 

 normal in every way except during the attacks. The black-crested 

 mangabey is, as nearly as can be determined, blind without obvious 

 gross defect in either eye. For almost a year, these three animals 

 have received daily doses of diphenylhydantoin sodium, which ap- 

 parently has suppressed the occurrence and severity of the seizures to 

 a minor degree. Ingestion of toxic quantities of lead has always been 

 considered a strong possibility in causing this condition, but it has 

 been determined that no lead-base paints have been used in the animal 

 areas, and an analysis of the water supply at the monkey house dis- 

 closed less than acceptable minimums of this element. 



A maned wolf {Chrysocyon jubatus), received from a dealer in 

 South America, died after a short illness in February 1961. The only 

 antemortem signs were inappetence and inanition leading to a comatose 

 state on the day before death. Antibiotics, canine antidistemper 

 serum, and intravenous therapy were without obsei-vable effect. A 

 necropsy performed immediately after death by the Pathology In- 

 stitute disclosed the following conditions : heartworm {D irofllaria sp.) , 

 lungworm {Filaroides osleri), and hookworm infestations; presence 

 of the giant kidney worm {Dioctophyma renale) ; parasitic nodules of 

 Spirocerca lupi in the aorta and other great vessels; large ulcerated 

 areas in the stomach; and negri bodies of rabies in microscopic 

 preparations of brain tissue. Just prior to death blood samples were 

 taken from this animal for blood-picture study and serology. The 

 interesting finding of these studies was the presence of serum anti- 

 bodies to the disease caused by Leptospira canicola. The serum titre 

 was a very high 1 :6400. 



A female maned wolf, which was obtained from the same source in 

 January 1960, died in August 1960, with the same antemortem signs. 

 The necropsy report describes only an infestation with the lungworm 

 Filaroides osleri. The central nervous system of this individual was 

 not examined because the carcass was requested for the U.S. National 

 Museum. 



Juvenile osteoporosis occurred in a pair of bobcats and a mountain 

 lion, all being. raised with the parents and all showing similar signs 

 of onset-lameness in one hind limb progressing to severe lameness and 

 ultimately posterior paralysis. Radiographs taken of one of the bob- 

 cats showed a fracture of the femur, a folding fracture of the pelvis, 

 and collapse of the lumbar vertebrae with resultant compression of 

 the spinal cord. Necropsy reports by Dr. Wayne Riser established the 

 condition as juvenile osteoporosis. For future cases he recommended 

 the addition of potassium iodide to the ration as well as increased 

 calcium and vitamin D (one-half teaspoonful daily of a solution of 50 

 mg. KI to 100 cc. of water) . 



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