and Laboratory Methods. 1905 



ature at which pain was felt was recorded. The author served as his own sub- 

 ject and tested the whole surface of the body. The results are graphically 

 mapped on rather striking plates. 



It was found that the two halves of the body are not equally sensitive to 

 thermal stimuli, the left side possessing a greater average sensitivity. The regions 

 bordering the median line of the body are less sensitive than the lateral surfaces, 

 while the body as a whole is more sensitive than the extremities. The distal and 

 the median regions of the extremities are more sensitive than the proximal and 

 lateral. Fundamentally warmth sensibility depends solely on the abundance of 

 the innervation ; secondarily it depends on the relative thickness of the stratum 

 corneum of the skin and on the effects of habit and use. r. p. 



Jordan, H. Die Physiologic der Locomotion This work is a Study of the physiology 

 bei Aplysia limacina. Inaug.-Dissertation, - ^, , e a . i ■ t 



Bonn. (Miinchen : Dnick von Oldenbourg) o^ the nervous System of Aplysia hnia- 

 1901. Pp. 51. Taf. I. (Also in Zeitschr. f. cilia with especial reference to the loco- 

 ^ motor movements of the animal. A 



series of extirpation experiments showed that parts of the body which are not 

 in connection with the pedal ganglia are in a state of persistent tonic contrac- 

 tion. Removal of the cerebral ganglia, the pedal ganglion being left intact, 

 causes persistent, rhythmical movements of the locomotor organs, which cannot 

 be inhibited. The principal function of the cerebral ganglion under normal 

 circumstances is to reduce the active condition of the pedal ganglion which 

 tends to cause persistent movement of the organism. r. p. 



NORMAL AND PATHOLOGICAL HISTOLOGY. 



JOSEPH H. PRATT, Harvard University Medical School. 



Books for Review and Separates of Papers on these Subjects should be Sent to Joseph H. Pratt, 

 Harvard University Medical School, Boston, Mass. 



Walz, K. Leukamie. Centralblatt fiir allge- The author presents a critical review 

 meine Pathologic u.pathologische Anatomic, ^f oo.S articles upon leukemia which 

 IZ: 967-1002, 1901. '^ 



have appeared since 1894. The sec- 

 tion devoted to the aetiology of the disease is especially interesting. The rapid 

 course which leukaemia runs certainly resembles that of an infectious disease. 

 The tonsillitis which frequently accompanies acute leukaemia or ulcers in the 

 intestine, described first by Askanazy, might well serve as portals of entry for 

 the infectious agent. Cabot (^Clinical Examination of the Blood, New York, 1900) 

 has reported a case of direct transmission of the disease from patient to nurse. 

 Bacteriological studies and the earlier inoculation experiments yielded negative 

 results. 



By means of special staining methods Lowit has demonstrated peculiar bodies 

 in the blood resembling protozoa which he regards as the cause of the disease. 

 He further supports his claim by the artificial production in animals of a disease 

 resembling leukaemia. As a specific stain he uses thionin followed by Lugol's 



