Journal of Applied Microscopy. 317 



from different parts of the body. This series shows also the virulence of the 

 streptococci and their capability of causing the death of the not pregnant animal 

 through spreading, by continuity, to other parts from the uterus. 



In the second series, it was shown that the steptococcus infection first brought 

 on abortion and later caused the death of the animal. 



In the third series, four rabbits were inoculated with the streptococcus and 

 all died in from three to eight days after inoculation. In sections from the 

 organs were found extensive changes as a result of the infection. 



The streptococcus, as this series shows, can produce a rapidly fatal infection 

 by spreading from the mucous membrane of the vagina to other parts. 



The fourth series of investigation is the most interesting inasmuch as the 

 animals operated on show that the streptococcus, introduced into the normal 

 vagina, may remain virulent for a long time, even causing severe infection, at 

 the delivery of offspring, occurring fort3^-five days after the introduction of the 

 streptococcus into the uninjured vagina. The disease caused by this infection 

 may appear in different forms ; at one time as an acnte general infection ; at 

 another, in the form of abscesses of the pelvis, periodphoritis, salpingitis, or 

 embolic suppuration in remote organs. The most important result obtained 

 from these investigations is the fact that the streptococci may remain in the 

 vagina for a long period of time, maintain their virulence, and, as was shown 

 by the experiment, be capable of causing disease forty-five days after their intro- 

 duction. They remained dormant until a lesion was formed through parturition, 

 but as soon as this was furnished infection took place. h. h. w. 



This work covers the examination of 



Kanthack, A. A. Influence of the Milk milk from sixteen dairies supplying 



Sladen, E. S. St. B. Supply on the Spread of ^ , . , ,-. • -^ .-r,! r i 



Tuberculosis. The Lancet. 74-78, 1899. Cambridge University. They found 



the milk received from nine, or 60 per 

 cent., was tuberculous. Of ninety guinea pigs inoculated with milk from all 

 these dairies twenty-three died, or 25.55 per cent. Some were inoculated with 

 the cream obtained by centrifugation, and others with the sediment at the 

 bottom of the centrifugal tube. Of those that died, thirteen were inoculated 

 with the cream, and ten with the sediment. In sixteen of the twenty-three 

 animals that died the tubercle bacillus was demonstrated in the organs of the 

 dead animals. h. h. w. 



Seybold, C. UeberdiedesinficirendeWirkung Seybold found from his experiments 

 des Metacresols Hauff im Vergleich zu that metacresol, orthocresol, paracresol, 

 Orthocresol, Pacacresol, Tricresol Schering, , . 111 1 ■ 1 • 



Phenol und Guajakol. Zeitsch. f. Hyg. 29: tricresol, phenol, and guaiacol, in 

 377-418, 1898. two per cent, solution, are equally 



ineffective and do not kill anthrax spores even after an exposure of 

 twenty-six days. P'rom his tables it is shown that the cresols possess a greater 

 germicidal effect against the vegetative microorganisms, staphylococcus pyrogenes 

 aureus, bacillus pyocyaneus, and bacillus prodigiosus, than do phenol and 

 guaiacol. Among the cresols the metacresol of Hauff is the most effective, para- 

 cresol comes next, orthocresol and tricresol act equally well and are the weakest. 

 Paracresol proved to be the most poisonous, and metacresol the least poisonous, 



