Journal of 



Applied Microscopy. 



Volume II. 



APRIL, 1899. 



Number 4 



Artificial Production of the Sickle Stage 

 of the Nucleolus. 



In most cytological studies the important question of correct interpretation is 

 constantly present, and great care must often be exercised in determining whether 

 the various appearances one meets are natural, or whether they have been pro- 

 duced artificially during the process of preparation and mounting, according to 

 the methods at present in vogue. One of these appearances, which has received 

 various interpretations, is the so-called sickle stage of the nucleolus, which 



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