380 Journal of Applied Microscopy. 



found a diffuse proliferation of lymphoid cells and of the endothelial cells of the 

 reticulum. Some of the latter showed phagocytic properties, as they contained 

 lymphoid cells, red blood corpuscles, and nuclear fragments. In the loose 

 mucous membrane of the tonsil the plasma cells of Unna were present in larger 

 numbers than normal. In four cases small abscesses in the interior of the folli- 

 cles were found. The growth of these abscesses was always in the direction of 

 the nearest crypt. Phagocytic cells were particularly numerous in the periphery 

 of these areas. The article is illustrated by six photomicrographs. 



R. M. p. 



Arnold, J. Zur Morphologie Intravascularen J- Arnold, as the result of his observa- 

 Geiimiung unci Pfropfbildung. Virchow's tions, believes that the blood platelets 

 Aichiv. 155: Heft i, iSgq. . , . i i i , , 



are formed from red blood corpuscles, 



and that fibrin formation and thrombosis are closely related to degenerative 

 changes in the red blood corpuscles. A simple diminution of size, leading to 

 the formation of microcytes, or to complete disappearance of the corpuscle, he 

 terms Erythrocytolysis. The extrusion of round refractive granules (" dust 

 bodies " of Miiller), and the separation at the periphery of small particles, he 

 terms Erythrocytorrhexis. Erythrocytoschisis is the term used to describe the 

 breaking up of red blood corpuscles into disc-like bodies. In the mesenteric 

 vessels of living animals he observed the formation of blood platelets from red 

 blood corpuscles by the last two forms of degeneration. This observation he 

 believes settles the question of their origin. In thrombosis, in rabbits, produced 

 by the inoculation of foreign bodies, and in both vital and agonal thrombi in 

 man, he observed in red blood corpuscles all three of these degenerative changes. 



R. M. p. 



r •! \\j x T-u /^i . r .1. r- 1 III a very extensive piece of work 

 Councilman, W. T, The Character of the Cel- •' ^ 



lular Exudate in Acute Keratitis of the Councilman makes a Study of the fol- 

 Rabbit. Jour. Boston Soc.- Med. Sc, 3: lowing points : (1) the character of the 



leucocytes which emigrate^; (2) from 

 what vessels do they come ? (o) the changes which they undergo in the course 

 of their migration ; (4) the changes which take place in the corneal corpuscles ; 

 (5) under what conditions, and how does the formation of new blood vessels 

 take place ? The principal irritant used was a pure culture of the staphylococcus 

 pyogenes aureus, introduced by scratching the center of the cornea with a knife. 

 Sections were examined from animals killed after 6, S, \'l, 18, 24, 36, and 48 

 hours, and daily up to the thirteenth day. Nitrate of silver, caustic potash, and 

 chloride of zinc were also used as irritants. 



Results : (1 and o) Three forms of leucocytes were found : first, a leucocyte 

 with fragmented nucleus, a limiting membrane, and a granular protoplasm stain- 

 ing intensely with eosin ; this cell corresponds to the polymorphonuclear leuco- 

 cyte of human blood. Second, a slightly granular leucocyte, with a horse-shoe 

 nucleus and no limiting membrane. Third, a lymphocyte with reticular nucleus 

 and a very narrow rim of protoplasm. The granular leucocytes appear early in 

 the inrtammatory process and are the most numerous. They travel between the 

 corneal fibers, and are often so drawn out as to stretch entirely across the field of 



