452 Journal of Applied Microscopy. 



The changes in the dorsal root ganglia were slight, consisting in rarefaction 

 of the chromatin, and changes in the shape and position of the nucleus. 



In the rabbit, changes very similar to those seen in the cord of man were 

 found. 



In rabbits killed on the twenty-third and sixty-fourth days, respectively, it 

 was thought that a process of restitution, as indicated by properly staining nuclei> 

 and a typical arrangement of newly formed Nissl's granules, could be made out. 



In prolonged cases a degeneration of peripheral nerves (sciatic and its 

 branches) was observed. The writer believes that these changes are quite 

 common in typhoid fever, and that to them are due the post-typhoid hyperaes- 

 thesiss and paralyses. r. m. p. 



.., . ^ ., , . ,, , , , In this study a primary melano-sarcoma 



Weiner, u. Ueber em Melanosarkom des -^ ^ •' 



Reciumsund die melanotischen Geschwiilste of the rectum in man is compared with 

 im Angemeinen. -Zeigler's Beitrage. 25: ^^^^ similar growths from the horse. 

 Heft II. ^ 



In the latter the growth does not pene- 

 trate deeply, and metastases are fewer in number. The growth is harder, 

 firmer, and the nodules are not so liable to softening. There is no perivascular 

 arrangement of the cells, all of which are pigmented. They are much less 

 malignant. Tests for iron to ascertain if the pigment was haematogenous in 

 origin, were negative. 



In man the blood vessels are involved either by a perivascular growth, 

 invasion of the vessel wall, or by actual penetration of the intima and projection 

 into the lumen. Metastases take place generally through the blood stream, and 

 are most common in the brain and the liver. a. m. 



Malkoff. Ueber die Bedeutung des trauma- Malkoff has succeeded in producing 

 tischen Verletzungen von Arterien (Quet- . . ^ n • ,i i 



schung, Dehnung) fur die Entwicklung des aneurisms experuiientally m the dog. 



wahren Aneurysmen und des Arterioskle- He USed twO methods, compression by 

 rose. Zeigler's Beitrage. 25: iSgg. , j. , ,. . ,, r 



lorceps and distension, as result of 



injecting salt solution. The most marked changes were obtained in the com- 

 pression experiments. Tears occurred in the intima, elastic plate and media, 

 and a spindle-shaped aneurism developed. After forty days the lumen became 

 normal, or smaller than normal. The lumen was markedly thickened and 

 showed new'ly developed elastic fibers. The elastic fibers appear to develop 

 from the periphery of the cells. There was an increase of connective tissue in 

 the media. Deposition of lime salts were found as early as twenty days after 

 injury. j. H. p. 



Pio Foa. Beitrage zum Studium des Knocken- In this study, which deals chiefly with 



marks. Zeigler's Beitrage. 25: Heft II. • ^ n t^i • ■, i tt i 



* " giant cells, Flemming s and Hermann s 



solutions were used as hardening agents ; and for staining, the methods 

 recommended by Van Gieson, Mallory, and Ramon y Cajal. Mallory's stain 

 gave the best results for the recticulum of the bone marrow, and for differen- 

 tiating the protoplasm of the giant cells. 



The giant cell is described as having three layers, an inner finely granular 

 protoplasm surrounding the nucleus, an intermediate layer of thick fibrillar 



