Journal of Applied Microscopy. 5-1 



On this medium, small round colonies develop which are at first white, but after 

 a few weeks become yellow. Gelatin is not liquefied and development is never 

 great. 



On potatoes a thick layer is formed which at the end of two weeks spreads 

 over the surface of the potato and becomes yellowish-brown in color. Grown 

 aerobically it soon loses its virulence. 



In only one experiment was an epithelial surface inoculated (the cornea). In 

 this case there was a marked proliferation of the epithelium with an appearance 

 of the organism in the cells and excessive irritation. 



Conclusions. — There are certain cancers, of very rare occurrence, which con- 

 tain cells filled with many bodies described by RufiEer and others as parasitic 

 protozoa. From their rare occurrence and their exceedingly acute course they 

 are thought to have a different origin than the ordinary cancer, but there is no 

 greater difference between them than between the acute and the chronic tubercle. 

 By suitable means the contents of these cells can be isolated and grown outside 

 the body. These cultures inoculated into a susceptible animal are capable of 

 producing death with the formation of tumors, of endothelial origin with one ex- 

 ception. From these proliferations pure cultures can be obtained, which, when 

 inoculated into susceptible animals, produce similar tumors. h. h. w. 



Novy, Frederick G., Sc. D., M. D., University of " Every medical student should re- 

 Michigan Laboratory Work in Piiysio- ^gj^g thorough drill in the laboratory, 

 logical Chemistry. Second edition, revised ° •' ' 

 and enlarged, with frontispiece and twenty- not merely in SO-called urine analysis, 

 four illustrations, pp. 326, 1898. Ann Arbor: ^^^ ;„ the broader field of physiolog- 

 George Wahr. , f j & 



ical chemistry. He should be taught to 



observe and to reason ; to correlate the facts brought out in the laboratory in 

 their relation to physiology, hygiene, and disease." 



The above, taken from the preface of this work, strikes the key-note of labo- 

 ratory work for medical students. It is to be regretted that all medical schools 

 do not require a knowledge of elementary chemistry for entrance. If this were 

 the case, the student would be better prepared for other work, and the time now 

 devoted to elementary chemistry could be given to a more extended study of 

 physiological and pathological chemistry. 



This volume starts with a chapter devoted to the study of " Fats," giving brief 

 explanatory descriptions of the source, the character, and composition of fats ; 

 the action of the various ferments upon them, and the various theories of absorp- 

 tion. With this introduction, the student is given directions for the performance 

 of nineteen experiments on fats and their decomposition products, which must 

 needs fix, and impart to the student, an amount of knowledge which will prove of 

 inestimable value. 



The second chapter is devoted to the " Carbohydrates," the Tollens classi- 

 fication being used. The preliminary descriptions contain a large amount of 

 information in a comparatively small space. The subjects covered in this 

 chapter are pentoses, hexoses, glucose, cane sugar, lactose, maltose, starch, 

 dextrin, glycogen, and cellulose, together with a brief description of the polar- 

 iscope, and its use as applied to the examination of sugars. The experiments 



