J. Smolak 



145 



described. Probably the form which the disorganised nucleus takes 

 may be dependent on the form of the cells (Figs. 13, 14). 



As to the nucleolus, the normal spherical or only slightly deformed 

 nucleus contains one or two easily distinguishable nucleoli. After 

 subsequent disorganisation we cannot discern such obvious nucleoli 

 in the nuclei. 



In addition to modifications of form of the nuclei marked changes 



Fig. 11. Palisade cell showing septum-like nucleus. 



Fig. 12. Palisade cell showing septum-like nucleus with irregular outlines. 



take place in the chromatin. The normal nucleus contains a conspicuous 

 network with numerous intensely stained chromatin granules. But as 

 it disorganises the nucleus always contains fewer and fewer granules. 

 There is strong evidence (see below) for the view that these grains 

 sometimes wander out from the nucleus into the cytoplasm. Cases 

 were found which were a distinct proof of this. The chromatin mani- 

 fests a tendency to accumulate on the periphery of the nucleus. It. is 

 possible that the grains move centrifugally and press against the nuclear 

 membrane, for we notice the chromatin grains accumulated close to 

 Ann. Biol, n 10 



