INDEX 



Ecology, bacterial, 15 

 Ehrlich's side-chain theory, 49 

 Electron microscopy, particle counts 



and infectivity, 22 

 Endotoxins, 102, 109 

 Enzyme formation, adaptive, 4, 55 

 Eosinophils, 117 



in disease, 136 



in proliferation, 93 



significance in immune reactions, 117 



see also Mesenchymal cells 

 Erythromyelosis, 177 

 Erythrophagocytosis, 144 

 Escherichia coli {E. coli), 71 



histidine-requiring, 1 1 



and 'permease', 13 



see a/50 Adaptive changes. Mutations 

 Evolutionary approach to immunity, 

 200 



Fibroblasts, 116 



Fleece mosaic in sheep, 166 



Fluorescent staining of antibody, 44, 



70, 109 

 Follicular lymphoma, 169, 178 

 Forbidden clones, see Clones 

 Forbidden patterns, see Clones 



Haemagglutination 



as evidence of infection, 18 



for virus isolation, 16 

 Haemolysis, immune, 64 

 Haemolytic anaemia, 43 



acquired, 126 



in agammaglobulinaemia, 143 



in lymphatic leukaemia, 1 78 

 Haemolytic streptococci, 156 

 Hashimoto's disease, 123-6 

 Hepatitis, lupoid, 125, 134 

 Histamine release, 133 

 Histidine-requiring E. coli, 1 1 

 Hodgkin's disease, 128, 168, 180 

 Homeostatic mechanism, 122, 128, 

 134, 140, 145, 193 



and elimination of forbidden 

 clones, 122 



and haemolytic anaemias, 130 



malfunction of, 156 

 Homograft immunity, 40, 41, 79, 88 

 Hypersensitivity 



and agammaglobulinaemia, 42 



to antigens, 37 



passive transfer of, 37, 41 



tuberculin, 40, 79 



to vaccine, 43 



Galactosidase, /?-, 4, 13, 71 



and 'permease', 13 

 Gamma globulin, 30, 52 



denatured, 134 



level in blood, 141 

 Genetic pool, 9 

 Genocopy, 51 



Giant-cell measles pneumonia, 154 

 Globulins 



a 2, 40 



abnormal in lymphatic leukaemia, 



179 

 and amino acids, 181 

 gamma, see Ganuna globulin 

 individuality in myelomatosis, 183 

 macro-, 126 

 in myelomatosis, 181 

 properdin, 39, 99 

 Goodness of fit of antigen and reaction 



site, 93 

 Graft intolerance, 89 

 Granuloma, tuberculous, 162 

 Granulomatous lesions, effect of zirco- 

 nium salts, 1 30 



Immune responses, 29 



classical antibody production, 38 



and eosinophils, 1 1 8 



hay-fever type, 38 



tuberculin type, 38 

 Immunity 



local, 83 



to virus diseases, 43 

 Inamunization, primary, 69 

 Immunological 'memory', 63, 79 

 Immunological reactivity, types of, 65 

 Incubation period of virus disease, 143 

 Indirect template theory, 51, 148 

 Infectious mononucleosis, 123, 128 

 Influenza virus, 16, 20, 75 



filamentous form, 19-20 



neurobiopic, 19 

 Information, cellular storage of, 1 20 

 Information problem, in differentia- 

 tion of 'self from' not-self, 36, 47 

 Inhibition, contact in tissue culture, 



194 

 Intestinal cell multiplication, 187 

 Intestinal viruses, 84 



205 



