The Renal Blood Flow 



81 



parable to the pryogen that too frequently invades intraven- 

 ous infusions of saline, glucose, etc. We do not yet know the 

 nature of this pyrogen, but its source may be the fragmented 

 bodies of contaminating yeast, mould or bacterial cells which 

 have grown upon the inulin during the process of manufac- 

 ture.'^ 



In any case, we soon discovered that whenever the pyro- 

 genic reaction, which consists of headache, lumbar pain, 

 nausea' and ultimate fever, was encountered renal hyperemia 

 invariably occurred. This fact led us to investigate the action 



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 180 



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02 

 100- 120 



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 eo' 



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MINOTES 140" 



FIGURE 4 

 Figure 4. Illustrating the renal hyperemia produced by the pyrexia! reaction. 

 Legend as in Figure 1. (From 6). 



of typhoid vaccine. As shown in Figure 4, after a short latent 

 period, which serves as a control period, both diastolic and 

 systolic pressure typically increase, this pressor phase usually 

 coinciding with the febril chill. As the chill passes the blood 



