juneir, i9i8 Effects of Chemicols on Virus of Mosaic Disease 637 



bacillus, according to Anderson and and McClintic/ does not appear to 

 be stronger than carbolic acid or cresol in its effect upon the infective 

 principle of the mosaic disease of tobacco. 



Acetone destroys the infective principle of the mosaic disease much 

 less readily than ethyl alcohol. The infective principle is destroyed 

 rather quickly in alcohol stronger than 50 to 55 per cent. Eighty per 

 cent strengths killed the virus in less than half an hour. 



Chloral hydrate in the writer's experiments did not appreciably affect 

 the infectivity of the virus. Benzoate of soda and quinine bisulphate 

 affected the virus but little under the conditions of the experiments. 

 Tannic acid appeared to be somewhat less effective than sodium tauro- 

 cholate or saponin. Naphthalene crystals, camphor, and thymol had no 

 appreciable effect. 



Formaldehyde in a 4 per cent strength destroyed the infective principle 

 very quickly. Glycerin, except in very strong concentrations, affects 

 the virus but little. 



When mixed with talc, kaolin, or soil, the virus frequently loses its 

 nfectious properties more quickly than when merely bottled without 

 the addition of any preservative. 



• Anderson, J. F., and McCijN'nc, T. B. op. at. 

 56114°— 18 3 



