BlooiJ I'd nisi te^. "^35 



houiogeneonsh- than do the uuatfected nuclei. The size of the 

 normal erythrocyte varies from 15.2 fi long by 3.7 /x vvide 

 to I'arely i\.'\ n lon^x l)y 4 /x wide. That of the infected cells 

 varies from '2'2 fi long by 14.2 /i wide up to 60 /i long by 

 28 /A wide, 35 to 55 /i being the more freque,nt le'ngths by 

 about 20 fx in width. Ttie parasite itself lies in the central 

 region of the host-cell alongside the host-nucleus. It is 

 gregarinoid in form. In size it nearly always exceeds that of 

 the host nucleus, and often that of the majority of the normal 

 erythrocytes. Tlius it varies from 13 //, long by 4 /a wide up 

 to 18.6 IX long by 5.6 //, wide, 14 to 16 /., in length by 5 /i 

 in width being the more frequent. All forms seen were spo- 

 ronts, no forms -showing the division stages of the sexual cycle 

 being found. Tlie body is fairly homogeneous, somewhat granu- 

 lar and blue (with Gieuisa smears) often fainter at one ex- 

 tremity than elsewhere. The nucleus is generally spherical, 

 pinkish with deeper stained almost reddish granules, some- 

 times distributed chiefly in a radial manner at the periphery, 

 biu often fairly regularly throughout the nucleus. It may be 

 central, but at times lies towards one extremity. The capsule 

 of the parasite is rarely seen (cf. Figs. 3, 4 and 10), but often 

 the whole parasite, whether capsule is jiresent or not, is seen 

 surrounded by a faint zone, limited by a definite thin line, 

 which appears to enclose the nucleus of the host-cell as well 

 as the [liirasite. Doubtless this area represents an area of 

 degenerated stroma similar to that shown in the case of 

 Karyolysus lacet tarum, though in this case no granulation is 

 observable. The curious appearance of the host nucleus shown 

 in Fig. 7, a blue-stained, kidney-shaped mass surrounding a 

 pink homogeneous centre, together with the degeneration of 

 the stroma, in other forms is certainly suggestive of an affinity 

 with Karyolysus. The hooked tail of the homogregarinoid 

 form is well seen in Fig. 11, in which also the host-cell nucleus 

 is markedly enlarged and altered in shape. In rare cases en- 

 larged cells were found, such as shown in Figs. 9a and 9b, in 

 which no parasite was visible. It is inqjrobable that these are 

 cells which have been vacated by a parasite, since they are 

 riOt fully enlarged, and are normal except in size and in the 

 enlarged nucleus. Fig 8 shows a curious appearance found in 



