Blood of A ustmliaii Anitnnh. \nr> 



cine," p. 67, where he remarks, in reference t<> slides stained with 

 Irietiisa. "They (eosinophile granules) do not toim as conspicuous 

 objects as specimens stained by Louis .Tenner's stain.". 



Nomenclature. 



These facts have given rise to a difficulty in arriving at a com- 

 pletely satisfactory method of naming the various forms of leu- 

 cocyte, and probably as Fantham (5) remarks, p. 726, " The 

 differences in opinion of the various investigators are explicable by 

 reference, to slight variations in the stains." 



In arriving at any satisfactory nomenclature it has been neces- 

 sary to compare the several methods employed by different investi- 

 gators. 



Erhlich, (6) dealing with human blood, distinguishes six normal 

 types— 1, Lymphocytes; 2. Large mononuclear leucocytes. Between 

 I and 2 he states there are no transitional forms. .'5. Transitional 

 forms derived from 2. 4. " Polynuclear " leucocytes. 5. Eosino- 

 phil cells. ('). Mast tells. In addition he describes various patho- 

 logical forms. 



Burnett (4) distinguishes five varieties of leucocyte in normal 

 blood — 1, Lymphocytes. 2. Large mononuclear and intermediate 

 forms between I and 2. .*$. Polymorphonuclear forms, or finely 

 granular oxyphils. In this group he includes those cells in the- 

 blood of birds which contain large spindle granules. 4. Eosino- 

 phils. 5. Mast, which he describes as coarsely granular basophiles, 

 but which I have usually found to be distinguished by their meta- 

 chromatic staining properties. He also notes many degenerate 

 forms of leucocyte, evidently present under fairly normal con- 

 ditions, such as swollen or irregular nuclei; degenerating nuclei; 

 ruptured cell bodies and pale nuclei, etc. ; beside many forms 

 found under pathological conditions, such as myelocytes, plasma 

 tells, and various abnormal kinds of erythrocytes. The blood 

 dust described by Burnett perhaps corresponds to the substance 

 attributed by Cullen (7) to the free granules of the mast cells, and 

 to which the same name is given. 



Cullen (7) describes four kinds of leucocytes in fishes and birds. 

 1. Small mononuclear, which closely resemble the corresponding 

 cells in man, and which I take to mean the lymphocytes of most 

 classifications. 2. Large mononuclears. 3. Eosinophils, in which 

 he distinguishes a granular form, and an oxyphilic spindle form, 

 in this respect differing from Burnett. From my own observations 



