84 DAVID G. MOULTON 



response. The bulbar spike discharges correlated closely with activity 

 assumed to be that of the primary olfactory neurones and recorded with 

 electrodes implanted in the region of the cribriform plate. For this 

 preparation stimulus-response curves derived from simultaneous recordings 

 of summated spike responses to amyl acetate at eight points in the bulb 

 and periphery, are presented. Differences between odorants in their 

 relative efficiency in stimulating different points in the bulbs and at the 

 periphery are also described. 



ACKNOWLEDGEMENTS 



This work was supported by a Grant from the United States Public 

 Health Service (B1083 C-5). 1 wish to thank Dr. L. M. Beidler for his 

 continued interest in and support of this work and to Drs. M. M. Mozell 

 and D. Tucker for many valuable discussions. 



REFERENCES 



Adey, W. R. 1953. An experimental study of the central olfactory connexions in a 



marsupial {Trichosurus vidpecida). Brain 76, 311-330. 

 Adrian, E. D. 1950. The electrical activity of the mammalian olfactory bulb. Electro- 



enceph. Clin. Neurophysiol. 2, 377-388. 

 Adrian, E. D. 1956. The action of the mammalian olfactory organ. /. Laryng. 70, 1-14. 

 Cajal, S. Ramon. 1911. Histologie dii systeme nerveiix de riwmme et des vertebres. 



Paris, Maloine, Vol. 2, chap. 28. 

 Cragg, B. G. 1962. Centrifugal fibres to the retina and olfactory bulb, and composition 



of the supraoptic commissures in the rabbit. Exp. Neurol. 5, 406^27. 

 Hernandez-Peon, R, Lavin, A., Alcocer-Cuaron and Marcelin, J. P. 1960. Elec- 

 trical activity of the olfactory bulb during wakefulness and sleep. Electroenceph. 



Clin. Neurophysiol. 2, 377-388. 

 Kerr, D. I. B. 1960. Properties of the olfactory efferent system. Aust. J. Exp. Biol. 



Med. Sci. 38, 29-36. 

 Kerr, D. I. B. and Hagbarth, K. E. 1955. An investigation of olfactory centrifugal fiber 



system. /, Neurophysiol. 18, 362-374. 

 Mozell, M. M. 1958. Electrophysiology of olfactory bulb. J. Neurophysiol. 21, 183-196. 

 Mozell, M. M. and Pfaffmann, C. 1954. The afferent neural process in odor perception. 



Ann. N. Y. Acad. Sci. 58, 98-108. 

 Tucker. This symposium. 

 Tucker, D. and Beidler, L. M. 1956. Autonomic nervous system influence on olfactory 



receptors. Amer. J. Physiol. 187, 637 (Abstr.) 

 VON Baumgarten, R., Green, J. D. and Mancia, M. 1962. Recurrent inhibition in the 



olfactory bulb. II. Effects of antidromic stimulation of commissural fibers. /. 



Neurophysiol. 25, 489-500. 

 Walsh, R. R. 1959. Olfactory bulb potentials evoked by electrical stimulation of the 



contralateral bulb. Amer. J. Physiol. 196, 327-329. 

 Yamamoto, C. and IwAMA. 1961. Arousal reaction of the olfactory bulb. Jap. J.Physiol. 



11, 335-345. 



