132 EMIL VON SKRAMLIK 



such as pressure, warm, cold and pain. Against this interpretation is the 

 fact that the taste buds are located very superficially in the gustatory area. 

 The different susceptibilities of the four gustatory substrates to anaesthetics 

 are thus determined only by the substrates themselves. 



SUMMARY 



On the basis of our findings the following can be stated : The efficiency 

 of the gustatory receptors is impaired by anaesthetics usually in varying 

 degrees. The substrate of bitter is most susceptible to anaesthetic. How 

 much the other three substrates are impaired depends mostly on the anaes- 

 thetic itself. The effect increases very fast and declines rapidly at first, then 

 slower, until after at most 80 min the tongue field has regained its original 

 state. The effect shows individual variations, both quantitatively and 

 qualitatively. 



It can generally be concluded that each principal sensation corresponds 

 to its own substrate. These substrates are fairly independent of each other. 

 This is shown by the following facts : Their recovery to the original 

 sensitivity takes quite different times, and complete recovery is sometimes 

 preceded by a period of hypersensitivity. 



