180 H. T. ANDERSEN, M. FUNAKOSHT AND Y. ZOTTERMAN 



on human subjects by various other authors. Our figures have been 

 arrived at by calculating an average value for each of the sugars, using all 

 of the experimental data obtained by recording from the whole chorda 

 tympani. In accordance with the practice of the previous investigators the 

 mean response of sucrose has been given a value of 100 arbitrary units, 

 and the averages for the other sugars has been adjusted in relation to this 



Quinine 0. 01 M 



Fig. 2. Electrical responses recorded from whole chorda tympani upon applica- 

 tion of 0.5 M sugar solutions to tongue. Responses to 0.5 m NaCl, 0.01 m quinine 

 and water are also shown. From top to bottom of each recording are shown 

 signal from dispensing burette, integrated response and time marks. Time in 



seconds. 



Standard. The comparison is shown in Table 1 (p. 183) where our figures 

 are listed together with those of Becker and Herzog (1906), Biester, Wood 

 and Wahlin (1925), Wahon (1926) and Fabian and Blum (1943). In the cases 

 where no quantitation has been attempted by the authors the sweetest 

 sugar has been identified with No. I, the next with No. II and so on. These 

 roman numbers are also given in parenthesis after the quantitative ones 

 for the sugars common in all of these investigations. 



In order to decide whether D-fructose and sucrose produce such large 

 responses in the unsplit chorda tympani by activating more fibres than the 

 other sugars, or by stimulating the proper receptors with a higher fre- 

 quency, we have to turn to an analysis of the impulse traffic in preparations 

 containing only one functional fibre. 



