H. T. ANDERSEN, M. FUNAKOSHI AND Y. ZOTTERMAN 



whereas when it followed after 0.5 m sucrose, it produced a marked deflec- 

 tion of the integrated curve (Fig. 9E). Even a sodium chloride solution of 

 only 0.2 m strength was able to strongly depress the response to a mixture 

 containing 0.5 m sucrose and 0.2 m NaCl, whereas this mixture ehcited a 

 pronounced second response when it followed after the 0.5 m sucrose solu- 

 tion (Fig. lOB and D). 



B 



0. 5M Sucrose 



0. 5M Mixture 



0. 5M Sucrose 0. 5M Sucrose + 0. 2M NaCl 



0. 2M NaCl 



0. 2M NaCl 



0. 2M NaCl 0. 5M Sucrose + 0. 2M NaCl 



Fig. 10. Depressing effect of 0.2 m sodium chloride on the response to mixture 

 containing 0.5 m sucrose and 0.2 m sodium chloride. Time in seconds. 



2. Responses of individual fibres. 

 may be grouped into three classes, 

 divided into three types, as shown : 



1. Specific sweet fibres 



2. Fibres responding to salt 



and sugar. 



3. Specific salt fibres. 



The functional single fibres studied 

 of which the second may be sub- 



I. Sugar response >salt response. 



II. Sugar response<salt response. 



l^III. Sugar response=salt response. 



(i) Sweet fibres. All of the fibres, by our criteria specific to sugar, were 

 inhibited by previous application of 0.5 m sodium chloride to the tongue. 

 This is illustrated in Fig. 1 1 where A shows the typical response of such a 

 fibre to 0.5 m sucrose. In Fig. 1 IB the inhibition of the sucrose-response by 



