CHEMICAL CODING IN TASTE — TEMPORAL PATTERNS 283 



180- 



120- 



^ D - Alanine 



o 100-1 

 a. 



60- 



40- 



20- 



Rat 



Chorda Tympani 



I / 



DL - Alanine 



Glycine 



Log Molar Concentration 



Fig. 9. Chorda tympani median time to maximum response magnitude following 

 chemical stimulation of the anterior tongue of the rat (based on eleven rats). 

 Ordinate represents time, in seconds from beginning of fluid movement in flow 

 system (2 sec required to reach tongue, tongue chamber empty approximately 

 8 sec later) to development of maximum (peak) response magnitude. Sum- 

 mator rise time (RC), 0.75 sec. Reproduced froni : Halpern, B. P., Bernard, 

 R. A. and Kare, M. R. 1961. Amino acids as gustatory stimuli in the rat. 

 /. Gen. Physiol. 45, 681. 



ACKNOWLEDGEMENTS 



The amino acid data were collected in collaboration with Dr. Rudy A. 

 Bernard. This research was supported in part by National Institutes of 

 Health — National Institute of Neurological Diseases and Blindness Grant 

 B-2184 ; United States Pubhc Health Service— National Institute of Mental 

 Health Post-Doctoral Research Fellowship MF-8790-C1, C2 ; and 

 Hendricks Research Grant No. 22. 



REFERENCES 



Beidler, L. M. 1953. Properties of chemoreceptors of tongue of rat. /. Neurophvsiol 



16, 595. 

 Beidler, L. M. 1955. The physiological basis of taste. ON R Symposium Report AC R-\, 



Symposium on Physiological Psychology. 

 Beidler, L. M. 1961. Taste receptor stimulation. Prog. Biophysics Biophys. Chem. 107. 

 FiSHMAN, I. Y. 1957. Single fiber gustatory impulses in rat and hamster. /. Cell. Comp. 



Physiol. 49, 319. 

 Halpern, B. P., Bernard, R. A. and Kare, M. R. 1962. Amino acids as gustatory 



stimuli in the rat. /. Gen. Physiol. 45, 681. 



