208 J. A. Giiruth: 



were al)seiit in otliers. The brain and spinal cord shovf no lesions 

 beyond at times a slight injection of the ventricles. The meninges 

 are generally normal, but in one naturally acquired case, and in 

 one deliberately conferred case, there was an abnormal quantity of 

 clear cerebro-spinal fluid present, especially around the medulla. 



The lungs in very acute cases show passive congestion ; the 

 pericardium contains a varying, though small, quantity of iloai- 

 serosity; the heart shows sub-epi- and sub-endo-cardial petechiae; 

 the blood coagulates readily with a firm clot and clear serum. 

 The stomach is generally normal, in only one case a few ecchymoses 

 being seen near the pylorus. The small intestines are invariably in 

 a muco-catarrhal condition with much serous effusion, coagulable 

 on exposure, and mixed with flocculi of shed epithelium. This is 

 found especially in the anterior part of the canal. In one case 

 small necrotic patches of the duodenal mucosa were observed. The 

 large intestines are generally tympanitic, but contain normal 

 ingesta. One case showed a large area of congestion and many 

 petechiae of the colon. The liver and kidneys are slightly con- 

 gested, and show cloudy swelling. Otherwise the organs are normal. 



Bacterioloyicdl Examination. 



Microscopical examination of the blood and other fluids, such as 

 cerebro-spinal fluid and pericardial serosity, as well as tissues, gave 

 always negative results. Blood secured from the heart and large 

 vessels in steiile pipettes and tubes immediately after death 

 coagulated readily, and remained sterile even at blood heat. Intra- 

 venous inoculation with such material gave negative results, so 

 that a living virus as the exciting cause was excluded, so far as 

 such experiments could determine. Fortunately the fodder wliich 

 had been fed to horses that had succumbed in an outbreak detailed 

 below had been secured by me. and tests with this gave interestinj^ 

 and surprising results. 



Observations on outbreak of Horse Paralysis in a 

 Melbourne stable. 



In the beginnine of November. 1911, I was advised bv Mi-. W. A 

 Kendall, n.AT.V.O., of a serious outbreak of disease affectiiMj' lliree 

 horses belonging to a dealer in one of the suburl)s. The thi-ee liorses. 

 of a very good draught type, became affected almost simultajieonslv. 

 and succuml)ed within 24 hours, in spite of treatment. Mi-. Ken- 



