RESISTANCE OF STREPTOCOCCI 83 



hydrogen peroxid sulution were found to be of very little 

 \alue. 



6. Iodine is very effective even in a high dilution and in the 

 presence of a moderate amount of albuminous material. In 

 a solution of 1 :2,(X)0, it destroyed all streptococci suspended 

 in water and in a solution of 1 : 1,000, all of them suspended 

 in an albuminous solution within one-fourth minute. It 

 would seem that it would be advisable to use very much 

 more dilute solutions of iodine than are ordinarily employed, 

 especially since the more concentrated solutions are both 

 irritating and destructive of tissue cells. 



7. The presence of albuminous fluid very markedly reduces 

 the germicidal effect of a number of agents, of which chlora- 

 min-T and thymol may be mentioned as examples. 



8. There does not seem to be a "specific" germicide for strep- 

 tococci. 



Acknowledgement is here made to the effect that most of the 

 technical work of this piece of research was done by Miss Margaret 

 Taylor. 



It is planned to continue this investigation with the hope of 

 finding one or more germicides which will destroy streptococci 

 without having any or at least onl}^ relatively slight harmful ef- 

 fects on the tissue cells. 



Bacteriological Laboratory, 



The State University. 



REFERENCES 



1. Lingelsheim, W. V.: Streptokokken, Handbuch der Pathogenen Mik- 



roorganismen, von Kolle and Wassermann, 4, 465, also, 

 Lingelsheim, W. V.: Aetiologie und Therapie der Streptococcus In- 

 fektionen, Beitr. z. exper. Therap., 1899, p. 1. 



2. Post, N. E. and Nicoll, H. K.: The Comparative Efficiency of Some 



Common Germicides, The Jom-nal A. M. A., Nov. 5, 1910, p. 1635. 



