134 TRY1'AN080MIASIS IN TIIK ANOLO-EO YTTIAN SfDAN 



Ugulida Kr|iiirts nf llic Kuyiil Socii'ty's ('ollllllissioli. In lliis liKiliki'V tllf sVMi|itiiiii8 

 undtTWi'iit a sudiliii aggraviitioii on February ll^tli, ami ilcalli oi-currf<l ratluT suddciilv. 

 Trypaiiosoiiii's swaniu'il in the IiIhimI, Imt nont' of tlic lonj^. tliin, \vliij)-lik<' funns were seen. 

 Tllf long forms all secmi'd to have iiK'rease<l in hreadtli, prolialilv as a preliminary to 

 longitudinal division. Typical short forms were present. 



/ 'oi:t -1110 rl trill. — Splei'n anil liver lioth enlarged. Jla-niorrhagie nieeration present in 

 the stnmacli. whieh eontaincd glairy mucUs and altered lilnod. Unfoit iiiiatcly smears 

 were not made. There was no pericardial or pleural etlusion. 



In a smear of a mi.xture of lilood and ccrehro-spinal fluid olitaincd from one of the foss.u 

 of the skull after renmval of the brain, trypanosonies, numerous bacteria, ami a short, stout 

 spirillum weri' found. The last looked like two thick clioiera vibrios joined end to end, 

 was rounded at the extremities, and iiuile unlike tiie spirillum found in gastric nieeration 

 (ride iii/rii). The animal had been ilead some jiours before the examination coidd be made. 



E.Xp. 4. — Jerboa J {.luculnx ijonloiii). Inocldated sidicutaueously with a few drops 

 of blood from Dog 1 on February ;?rd. inu"). This aninial. which liiirbnun d tlie Inenio- 

 gregarine alriady de.scrilied, became very ill after forty-eigiit hours and was chloroformed. 

 No evidence of infection with trypanosonies was found post-mortem. 



Exp. 5. — Gerbil 1 [(lirhillns p!l<J<n'<Jii'<, the common desert mouse). Feluiiarv :!rd. 



liiiKulatcd subcutaiieously witli a few ilrops of bl I fiuni Iln^; 1. This mouse was e.xamined 



several times with negative results. At a later period it was re-inij<ulatt'd from Dog 2, and 

 still lati'r from ])og M, owing to an error. (/•/</<• tal)le). 



It deveUiped trypanosomiasis and died during the night. Sluggish and degenerating 

 trypanosonies were found in tlic In art's 



blood. There was no gastric ulcera- _ Xl ^5 

 tion. The experiment was unsatis- ^^ ^D 1^ 

 factory owing to tlic mulliide inocula- ^^ ^^ 

 tions performed. Tlie blood showed ^ ^^^ ^Bk 

 both forms of tiypaiiosonie, and in \W ^ ^i -SL 

 this case, as in that of other ijn-liih^ ^kfl^ ® '^^^V' O ^^ 

 there was noticed an increase in length '*»^ ^^ __ ^ ^^ 

 in tliat part nf llir long t rypanosoiues ^ J^ ^ ' L. ^^ ^k ^^< 

 extending behind the centrosonie (Fig. A" ^^^^P^- ^^ A 



69). lu some instances the nieasure- 



lueiit from the posterior end to the 



centre of the centrosome was as much 



as 4"2 ft approaching the appearance & 



found in 7'. /.ein'sl. This portion of 



the body in ifeMla is occasioiiallv 



curved. 



Exp. Ij. Dog 3. — Inoculated sub- 

 cutaiieously on February l><th. with 2 e.c. blood fnuii Dog 2. Trypanosonies weiv found 

 in the blood on 2.'Jtli February, lilDf). This dog iv.-.ived intravenous injections of 

 chrysoidine, and will be mentioned later. J)catli occurred on March :^rd. Slight corneal 

 opacity had been noticed during life. At the autop.sy the spleen was found to !..■ cidargeil, 

 and the folli(des prominent on the surface. The liver was enlarged ami congested. 



The kidney exhibited signs of subacute nephritis, the capsule being slightly adherent. 



'Si vV 



I'h.. t»3.— Kl>K.MS IS OkKHIL. NuTH lung rt►^TKKI(^K KNIi (X K3.1 diaill.) 



